多囊卵巢综合征与健康相关生活质量各领域的负向可变影响相关：来自荟萃分析的证据。

Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis.

机构信息

Department of Obstetrics and Gynecology, National Key Laboratory and Unit of Infertility, Clinical Trial Base, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China.

出版信息

Fertil Steril. 2011 Aug;96(2):452-8. doi: 10.1016/j.fertnstert.2011.05.072. Epub 2011 Jun 24.

DOI:10.1016/j.fertnstert.2011.05.072

PMID:21703610

Abstract

OBJECTIVE

To systematically review the literature to identify the impact of polycystic ovary syndrome (PCOS) on specific health-related quality of life domains.

DESIGN

Meta-analysis.

SETTING

N/A.

PATIENT(S): The outcomes of 423 patients and 285 controls from 5 articles that used the Short Form 36 (SF-36) questionnaire were used for meta-analysis.

INTERVENTION(S): N/A.

MAIN OUTCOME MEASURE(S): The SF-36 dimensions including physical function, physical role function, body pain, general health, vitality, social function, emotional role function, and mental health were evaluated.

RESULT(S): Compared with controls, women with PCOS had lower scores in all SF-36 dimensions: physical function (mean differences [MD], -5.46; 95% confidence intervals [CI], -8.52, -2.41), physical role function (MD, -5.76; 95% CI, -8.49, -3.03), body pain (MD, -4.55; 95% CI, -7.99, -1.11), general health (MD, -11.34; 95% CI, -19.53, -3.15), vitality (MD, -15.14; 95% CI, -17.43, -12.84), social function (MD, -15.95, 95% CI, -18.57, -13.33), emotional role function (MD, -23.86; 95% CI, -27.51, -20.21), and mental health (MD, -13.83; 95% CI, -16.13, -11.53).

CONCLUSION(S): The meta-analysis showed that women with PCOS score lower in each dimension of the SF-36, mostly in the emotional role function.

摘要

目的

系统回顾文献，确定多囊卵巢综合征（PCOS）对特定健康相关生活质量领域的影响。

设计

荟萃分析。

环境

无。

患者

使用简明 36 健康状况调查问卷（SF-36）的 5 篇文献中的 423 名患者和 285 名对照者的结局用于荟萃分析。

干预措施

无。

主要观察指标

SF-36 维度包括身体功能、身体角色功能、身体疼痛、总体健康、活力、社会功能、情绪角色功能和心理健康。

结果

与对照组相比，PCOS 女性在所有 SF-36 维度的得分均较低：身体功能（平均差异[MD]，-5.46；95%置信区间[CI]，-8.52，-2.41）、身体角色功能（MD，-5.76；95% CI，-8.49，-3.03）、身体疼痛（MD，-4.55；95% CI，-7.99，-1.11）、总体健康（MD，-11.34；95% CI，-19.53，-3.15）、活力（MD，-15.14；95% CI，-17.43，-12.84）、社会功能（MD，-15.95；95% CI，-18.57，-13.33）、情绪角色功能（MD，-23.86；95% CI，-27.51，-20.21）和心理健康（MD，-13.83；95% CI，-16.13，-11.53）。