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女性健康研究(WENDY)——一项基于人群的研究方案,评估35岁左右女性的妇科和代谢健康状况。

Women's Health Study (WENDY)-a protocol of a population-based study assessing gynecological and metabolic health in women in their mid-30s.

作者信息

Piltonen Terhi T, Ohtamaa Maria, Arffman Riikka K, Vuokila Lotta, Hurskainen Elisa, Männikkö Minna, Huilaja Laura, Sinikumpu Suvi-Päivikki, Rautio Tero, Kilpivaara Katariina, Jokelainen Jari, Kiviniemi Eetu, Pinola Pekka, Törnävä Minna, Komsi Elina, Kangasniemi Marika H, Rajecki Maria, Luiro Kaisu, Kinnunen Jenni, Savukoski Susanna M

机构信息

Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Centre, University of Oulu, Oulu University Hospital, Oulu, Finland.

Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland.

出版信息

Am J Epidemiol. 2025 Mar 4;194(3):598-607. doi: 10.1093/aje/kwae230.

DOI:10.1093/aje/kwae230
PMID:39098824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11879528/
Abstract

The Women's Health Study (WENDY) was conducted to improve insights into women's health and health burden. It provides a unique, comprehensive data source that can be broadly utilized to understand gynecological symptoms, diseases, and their relation to metabolic and overall health more deeply in a population-based setting. The study was conducted in Finland from May 2020 to October 2022. It included 1918 women (33-37 years old) who were born in northern Finland between July 1985 and December 1987. Data collection comprised one 3- to 4-hour study visit that included clinical measurements, biological samples, ultrasound examinations and an extensive questionnaire on gynecological and reproductive history, physical and mental health, quality of life, lifestyles, current life situations, health awareness, and opinions. The study also included a menstrual cycle follow-up and cognitive testing up to 3 months via a mobile application. Given that all participants' data can be linked to all Finnish national registers, and the Northern Finland Birth Cohort participants' data can be linked to the birth cohort data set collected from gestational week 24 onward, WENDY study forms one of the largest data sets worldwide to investigate gynecological and metabolic health burden in women.

摘要

女性健康研究(WENDY)旨在增进对女性健康及健康负担的了解。它提供了一个独特、全面的数据源,可广泛用于在基于人群的背景下更深入地了解妇科症状、疾病及其与代谢和整体健康的关系。该研究于2020年5月至2022年10月在芬兰进行。研究对象包括1918名1985年7月至1987年12月出生在芬兰北部的女性(33 - 37岁)。数据收集包括一次3至4小时的研究访问,内容涵盖临床测量、生物样本采集、超声检查以及一份关于妇科和生殖病史、身心健康、生活质量、生活方式、当前生活状况、健康意识和观点的详尽问卷。该研究还通过移动应用程序对月经周期进行长达3个月的随访和认知测试。鉴于所有参与者的数据都可与所有芬兰国家登记册相关联,且芬兰北部出生队列参与者的数据可与从妊娠第24周起收集的出生队列数据集相关联,WENDY研究构成了全球最大的数据集之一,用于调查女性的妇科和代谢健康负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/c5190161663d/kwae230f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/18160c232dac/kwae230f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/0bdfb27ba01b/kwae230f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/c5190161663d/kwae230f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/18160c232dac/kwae230f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/0bdfb27ba01b/kwae230f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f7/11879528/c5190161663d/kwae230f3.jpg

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