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腰椎管狭窄症手术后的再次手术。

Reoperations after surgery for lumbar spinal stenosis.

机构信息

Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.

出版信息

World Neurosurg. 2011 May-Jun;75(5-6):737-42. doi: 10.1016/j.wneu.2010.10.043.

Abstract

OBJECTIVE

To study the indication for reoperations after lumbar decompression, the factors predisposing to redo operations, and the effect of prior instrumentation on developing adjacent level stenosis requiring reoperation.

METHODS

Kaplan-Meier analysis was used to compare the median interval to first reoperation. Cox regression was used for multivariate analysis of time to first reoperation.

RESULTS

Of 335 patients who underwent surgery for lumbar spinal stenosis, 63 (18%) underwent instrumentation in addition to decompression. There were 50 reoperations performed in 44 patients (13%). Of these 50 reoperations, 26 were at the same level, 14 were at the same level plus an adjacent level, and 10 were at an adjacent level. In 21 reoperations, the indication was adjacent level spinal stenosis; in 16, adjacent level spinal stenosis plus instability; in 9, instability alone; and in 4, disc problem. The risk of reoperation was higher among male patients (hazard ratio [HR] 1.2, 95% confidence interval [CI] 0.586-2.635) and in patients with prior instrumentation (HR 1.7, 95% CI 0.684-4.640). There was no statistical association between prior instrumentation and subsequent risk of reoperation (P = 0.12). There was no association between prior instrumentation and development of adjacent level stenosis requiring reoperation (P = 0.473).

CONCLUSIONS

Many patients with spinal stenosis undergo instrumentation because of instability. Most patients in this study underwent reoperation at the same level, and the most common pathology was spinal stenosis. The risk of reoperation was lower in older patients (≥65 years old). Although there was a trend that the risk of reoperation was higher among patients with prior instrumentation, it did not reach statistical significance. In this study, there was no association between prior instrumentation and adjacent level stenosis requiring reoperation. These findings need to be evaluated further in randomized trials.

摘要

目的

研究腰椎减压术后再次手术的适应证、易导致再次手术的因素,以及既往内固定对发生需要再次手术的邻近节段狭窄的影响。

方法

采用 Kaplan-Meier 分析比较首次再次手术的中位间隔时间。采用 Cox 回归进行首次再次手术时间的多因素分析。

结果

在 335 例接受腰椎椎管狭窄症手术的患者中,63 例(18%)除减压外还进行了器械固定。44 例患者(13%)共进行了 50 次再次手术。其中,26 次在同一水平,14 次在同一水平加邻近水平,10 次在邻近水平。21 次手术的适应证为邻近节段脊柱狭窄症,16 次为邻近节段脊柱狭窄症加不稳定性,9 次为单纯不稳定性,4 次为椎间盘问题。男性患者(危险比[HR]1.2,95%置信区间[CI]0.586-2.635)和有既往器械固定的患者(HR 1.7,95%CI 0.684-4.640)再次手术的风险较高。既往器械固定与再次手术的风险之间无统计学关联(P=0.12)。既往器械固定与需要再次手术的邻近节段狭窄症的发生无关联(P=0.473)。

结论

许多脊柱狭窄症患者因不稳定性而接受器械固定。本研究中的大多数患者在同一水平进行了再次手术,最常见的病变是脊柱狭窄症。年龄较大的患者(≥65 岁)再次手术的风险较低。尽管有趋势表明既往有器械固定的患者再次手术的风险较高,但未达到统计学意义。在本研究中,既往器械固定与需要再次手术的邻近节段狭窄症之间无关联。这些发现需要在随机试验中进一步评估。

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