Croucher Institute of Environmental Sciences, Department of Biology, Hong Kong Baptist University, Hong Kong, PR China.
Chemosphere. 2011 Sep;85(2):277-83. doi: 10.1016/j.chemosphere.2011.06.002. Epub 2011 Jun 25.
Perfluorinated compounds (PFCs) are man-made fluoro-surfactants that are identified as global pollutants and can pose health risks to humans and wildlife. Two aspects of risk assessment were conducted in this study, including exposure and response. Exposure was estimated by using the concentrations of PFCs in fish and applying standard exposure factors. Among different PFCs, PFOS, PFOA, PFNA, PFDA, PFUdA and PFTrDA were detected. Total concentrations of PFC in fish ranged from 0.27-8.4 ng g(-1) to 0.37-8.7 ng g(-1) respectively in Hong Kong and Xiamen. The calculated hazard ratio (HR) of PFOS for all fish was less than 1.0. However, the HR for mandarin fish in Hong Kong and bighead carp, grass carp and tilapia in Xiamen, had HR values of approximately 0.5, indicating that frequent consumption of these 4 more contaminated fish species might pose an unacceptable risk to human health. Our data support the notion that the released/disposed chemical pollutants into water systems make fish a source of environmental toxicants to humans. The risks and potential effects of PFCs to health of coastal population in the Pearl River Delta are of concern.
全氟化合物（PFCs）是人为的含氟表面活性剂，被认为是全球性污染物，可能对人类和野生动物的健康构成威胁。本研究进行了风险评估的两个方面，包括暴露和反应。暴露是通过使用鱼类中的 PFC 浓度并应用标准暴露因子来估计的。在不同的 PFC 中，检测到 PFOS、PFOA、PFNA、PFDA、PFUdA 和 PFTrDA。香港和厦门鱼类中 PFC 的总浓度分别在 0.27-8.4ng/g 到 0.37-8.7ng/g 之间。对于所有鱼类，PFOS 的危害比（HR）均小于 1.0。然而，香港的鳜鱼和厦门的鳙鱼、草鱼和罗非鱼的 HR 值约为 0.5，这表明经常食用这 4 种污染程度更高的鱼类可能对人类健康构成不可接受的风险。我们的数据支持这样一种观点，即释放/处置到水系中的化学污染物使鱼类成为人类环境毒物的来源。珠江三角洲沿海地区人口接触 PFCs 的风险和潜在影响令人关注。
