Mattout C, Mege J L, Mattout P, Fourel J, Monnet V
Faculté de Chirurgie Dentaire de Marseille.
J Parodontol. 1990 May;9(2):189-93.
It is generally assumed that early onset forms of periodontal disease (including Juvenile and Rapidly Progressive Periodontitis) are associated with a defect in neutrophil behaviour. We have investigated neutrophil functions in patients with Juvenile (J.P.) and Rapidly Progressive Periodontitis (R.P.P.). In the group of J.P. patients the directed mobility (FMLP and zymosan activated plasma) is significantly decreased. The superoxide generation in response to FMLP decreases while the PMA response is normal. In the group of R.P.P. patients no significant abnormality has been reported.
一般认为，牙周病的早发型（包括青少年牙周炎和快速进展性牙周炎）与中性粒细胞行为缺陷有关。我们已经研究了青少年牙周炎（J.P.）和快速进展性牙周炎（R.P.P.）患者的中性粒细胞功能。在J.P.患者组中，趋化运动（FMLP和酵母聚糖激活血浆）显著降低。对FMLP的超氧化物生成减少，而对佛波酯（PMA）的反应正常。在R.P.P.患者组中，未报告有明显异常。
