人乳头瘤病毒假病毒作为DNA传递载体。
HPV pseudovirions as DNA delivery vehicles.
作者信息
Ma Barbara, Roden Richard B S, Hung Chien-Fu, Wu T C
出版信息
Ther Deliv. 2011 Apr;2(4):427-30. doi: 10.4155/tde.11.28.
Abstract
"The ability of HPV pseudovirions to efficiently deliver DNA into cells suggests several potential applications in basic biology, including the characterization of virion biology and measurement of protective neutralizing antibody titers in vitro and in vivo, as well as their employment for more direct medical applications".
摘要
人乳头瘤病毒假病毒高效地将DNA递送至细胞的能力提示了其在基础生物学中的几种潜在应用，包括病毒体生物学特性的表征、体内外保护性中和抗体滴度的测定，以及将它们用于更直接的医学应用。
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