Saini S S, Maiti N K, Sharma S N
Department of Veterinary Bacteriology and Virology, Punjab Agricultural University, Ludhiana, India.
Trop Anim Health Prod. 1990 Aug;22(3):165-9. doi: 10.1007/BF02241010.
The immune response of chicks to oral vaccination with HP1-strain of fowl pox virus was studied using intracellular virus alone or a combination of intra and extracellular viruses. The first and second vaccinations were done at four days and 25 days of age, respectively. In both groups the birds showed 50% protection against challenge virus at 32 days of age while no immunity was recorded at 95 days of age. The serum IgG concentration in both the vaccinated groups was comparable and it was significantly higher (P less than 0.05) than the control birds one week after revaccination. The serum haemolytic complement activity in both the vaccinated groups was significantly lower (P less than 0.05) than the control birds.
利用单独的细胞内病毒或细胞内与细胞外病毒的组合，研究了雏鸡对鸡痘病毒HP1株口服疫苗接种的免疫反应。首次和第二次疫苗接种分别在4日龄和25日龄进行。两组鸡在32日龄时对攻击病毒均表现出50%的保护作用，而在95日龄时未记录到免疫力。再次接种疫苗一周后，两个接种组的血清IgG浓度相当，且显著高于（P<0.05）对照鸡。两个接种组的血清溶血补体活性均显著低于（P<0.05）对照鸡。
