比马前列素治疗全秃型斑秃。
Bimatoprost in the treatment of eyelash universalis alopecia areata.
作者信息
Vila Teresa Ojeda, Camacho Martinez Francisco M
机构信息
Universital Hospital Virgen Macarena, Sevilla, Spain.
出版信息
Int J Trichology. 2010 Jul;2(2):86-8. doi: 10.4103/0974-7753.77511.
OBJECTIVES
To evaluate topical bimatoprost for eyelash growth in patients with alopecia areata (AA).
DESIGN
A 1-year retrospective study, bilateral eyelash alopecia.
MATERIALS AND METHODS
Forty-one subjects with AA universalis without ocular disease applied 0.03% bimatoprost to the eyelid margin once a day over the course of 1 year.
RESULTS
Thirty-seven subjects completed the study, one patient was eliminated due to conjunctivitis at the beginning of treatment, two patients developed conjunctivitis after 6 months of treatment, and a fourth did not follow directions. Researchers evaluated patients' eyelash growth every 4 months. We observed complete growth in 24.32%, moderate growth in 18.91%, slight growth in 27.02% and without response in 29.72%.
CONCLUSION
Bimatoprost may be effective and safe in the treatment of eyelash AA. 43.24% of the patients had an acceptable cosmetic response (total and moderate growth).
LIMITATIONS
Design without control.
目的
评估局部使用比马前列素对斑秃（AA）患者睫毛生长的效果。
设计
一项为期1年的回顾性研究，双侧睫毛秃发。
材料与方法
41例泛发性斑秃且无眼部疾病的受试者在1年时间里每天一次在眼睑边缘涂抹0.03%的比马前列素。
结果
37例受试者完成了研究，1例患者在治疗开始时因结膜炎退出，2例患者在治疗6个月后出现结膜炎，第4例未遵循用药说明。研究人员每4个月评估患者的睫毛生长情况。我们观察到睫毛完全生长的占24.32%，中度生长的占18.91%，轻度生长的占27.02%，无反应的占29.72%。
结论
比马前列素治疗斑秃性睫毛缺失可能有效且安全。43.24%的患者有可接受的美容效果（完全生长和中度生长）。
局限性
无对照设计。
Zotero 插件