Bodh Sonam A, Kumar Vasu, Raina Usha K, Ghosh B, Thakar Meenakshi
Department of Ophthalmology, Guru Nanak Eye Center, Maulana Azad Medical College, New Delhi - 110 001, India.
Oman J Ophthalmol. 2011 Jan;4(1):3-9. doi: 10.4103/0974-620X.77655.
Glaucoma is seen in about 20% of the patients with uveitis. Anterior uveitis may be acute, subacute, or chronic. The mechanisms by which iridocyclitis leads to obstruction of aqueous outflow include acute, usually reversible forms (e.g., accumulation of inflammatory elements in the intertrabecular spaces, edema of the trabecular lamellae, or angle closure due to ciliary body swelling) and chronic forms (e.g., scar formation or membrane overgrowth in the anterior chamber angle). Careful history and follow-up helps distinguish steroid-induced glaucoma from uveitic glaucoma. Treatment of combined iridocyclitis and glaucoma involves steroidal and nonsteroidal antiinflammatory agents and antiglaucoma drugs. However, glaucoma drugs can often have an unpredictable effect on intraocular pressure (IOP) in the setting of uveitis. Surgical intervention is required in case of medical failure. METHOD OF LITERATURE SEARCH: Literature on the Medline database was searched using the PubMed interface.
葡萄膜炎患者中约20%会出现青光眼。前葡萄膜炎可为急性、亚急性或慢性。虹膜睫状体炎导致房水流出受阻的机制包括急性、通常可逆的形式（如小梁间隙炎症成分积聚、小梁薄片水肿或睫状体肿胀导致的房角关闭）和慢性形式（如前房角瘢痕形成或膜增生）。仔细询问病史和随访有助于区分类固醇性青光眼和葡萄膜炎性青光眼。虹膜睫状体炎合并青光眼的治疗包括使用甾体和非甾体抗炎药以及抗青光眼药物。然而，在葡萄膜炎的情况下，青光眼药物对眼压（IOP）的影响往往不可预测。药物治疗失败时需要手术干预。文献检索方法：使用PubMed界面在Medline数据库中检索文献。
