Zimmerman R, Hammarström S
Urol Res. 1978;6(4):215-9. doi: 10.1007/BF00262621.
Carcinoembryonic antigen (CEA)-like material from urinary bladder carcinoma was purified and compared with the immunological and physico-chemical properties of CEA isolated from colon cancer. After immunoadsorbent purification, the final step in a purification procedure similar to that adopted for colon cancer CEA, two main molecular species were identified: 1) Material identical with colon cancer CEA with respect to molecular size, PCA solubility, ability to bind to Con A, and most important the ability to bind to specific monkey anti-CEA serum. 2) Material with the same chromatographic and immunological properties as NCA.
从膀胱癌中提纯出癌胚抗原（CEA）样物质，并与从结肠癌中分离出的CEA的免疫和物理化学特性进行比较。在采用与提纯结肠癌CEA相似的提纯程序，经免疫吸附提纯后，鉴定出两种主要分子类型：1）在分子大小、对PCA的溶解性、与刀豆球蛋白A结合的能力方面，最重要的是在与特异性猴抗CEA血清结合的能力方面，与结肠癌CEA相同的物质。2）具有与NCA相同的色谱和免疫特性的物质。
