足细胞生物学与床旁诊疗。
Podocyte biology for the bedside.
机构信息
Division of Nephrology, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
出版信息
Am J Kidney Dis. 2011 Nov;58(5):835-45. doi: 10.1053/j.ajkd.2011.03.033. Epub 2011 Jun 29.
Abstract
The explosion of podocyte biology during the last decade has radically altered our views on the pathophysiologic process of proteinuria, glomerular disease, and progressive kidney disease. In this review, we highlight some of these landmark findings, but focus on recent advances in the field and implications for translating this biology into therapy for podocyte diseases.
摘要
过去十年间，足细胞生物学的飞速发展彻底改变了我们对蛋白尿、肾小球疾病和进行性肾病病理生理过程的认识。在这篇综述中，我们强调了其中一些具有里程碑意义的发现，但重点关注了该领域的最新进展及其对将这些生物学发现转化为足细胞疾病治疗的意义。
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