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局限性掌跖角化不全症:1例意大利病例报告

Circumscribed palmar or plantar hypokeratosis: report of an italian case.

作者信息

Tosi D, Sala F, Crosti C

机构信息

Department of Anesthesia, Intensive Care and Dermatological Sciences, Università degli Studi di Milano, IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan via Pace 9, Milan, 20122, Italy.

出版信息

Indian J Dermatol. 2011 Mar;56(2):211-3. doi: 10.4103/0019-5154.80421.

DOI:10.4103/0019-5154.80421
PMID:21716552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3108526/
Abstract

Circumscribed palmar or plantar hypokeratosis is a rare benign epidermal malformation of the skin. Clinically it shows asymptomatic, well-circumscribed, and depressed erythema persisting for many years on the palms or soles. Its main histopathologic feature shows a characteristic epidermal depression with an abrupt decrement in the thickness of the stratum corneum, with a sharp stair between normal and involved skin. We describe a case of a 68-year-old woman who presented with an erythematous, asymptomatic, well-circumscribed, depressed patch, on the right thenar eminence which had been present for years.

摘要

局限性掌跖角化不全症是一种罕见的皮肤良性表皮畸形。临床上,它表现为手掌或足底出现无症状、边界清晰且凹陷的红斑,持续多年。其主要组织病理学特征为特征性的表皮凹陷,角质层厚度突然变薄,正常皮肤与受累皮肤之间有明显的阶梯状变化。我们报告一例68岁女性病例,其右手鱼际隆起处出现一个多年存在的红斑性、无症状、边界清晰的凹陷斑块。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7087/3108526/6924158e494e/IJD-56-211-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7087/3108526/8268f1106147/IJD-56-211-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7087/3108526/6924158e494e/IJD-56-211-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7087/3108526/8268f1106147/IJD-56-211-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7087/3108526/6924158e494e/IJD-56-211-g002.jpg

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本文引用的文献

1
Premalignant circumscribed palmar hypokeratosis: a new form of circumscribed palmar hypokeratosis? Case report and literature review.局限性掌跖角化不足症恶变前期:局限性掌跖角化不足症的一种新形式?病例报告及文献复习。
Dermatology. 2010;220(2):143-6. doi: 10.1159/000264607. Epub 2009 Dec 2.
2
Circumscribed palmar hypokeratosis: partial remission by photodynamic therapy.局限性掌部角化不全:光动力疗法部分缓解
Br J Dermatol. 2007 Oct;157(4):804-6. doi: 10.1111/j.1365-2133.2007.08053.x. Epub 2007 Jun 26.
3
Circumscribed palmar hypokeratosis: successful treatment with cryotherapy.
局限性手掌角化不全:冷冻疗法治疗成功
J Eur Acad Dermatol Venereol. 2007 Mar;21(3):420-1. doi: 10.1111/j.1468-3083.2006.01908.x.
4
Circumscribed palmar hypokeratosis induced by papilloma virus type 4.4型乳头瘤病毒引起的局限性掌部角化不全症
J Am Acad Dermatol. 2006 May;54(5):908-9. doi: 10.1016/j.jaad.2005.11.1081.
5
Circumscribed palmar hypokeratosis: new observations.
Am J Dermatopathol. 2006 Apr;28(2):112-6. doi: 10.1097/01.dad.0000193825.90552.4e.
6
Circumscribed palmar hypokeratosis: clinical evolution and ultrastructural study after prolonged treatment with topical calcipotriol.局限性掌部角化减退症:外用卡泊三醇长期治疗后的临床演变及超微结构研究
J Eur Acad Dermatol Venereol. 2005 Jul;19(4):491-4. doi: 10.1111/j.1468-3083.2005.01197.x.
7
[Circumscribed acral hypokeratosis].[局限性肢端角化减退症]
Hautarzt. 2004 Nov;55(11):1060-3. doi: 10.1007/s00105-004-0778-4.
8
Circumscribed palmar or plantar hypokeratosis: a distinctive epidermal malformation of the palms or soles.
J Am Acad Dermatol. 2002 Jul;47(1):21-7. doi: 10.1067/mjd.2002.120466.