Morellón Baquera Raquel, Allegue Rodríguez Francisco, Conde Ferreirós Marta, Alvarez-Sarria Miguel, Fachal Bermúdez Carmen
Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, España.
Servicio de Dermatología, Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, España.
Rev Esp Patol. 2022 Jul-Sep;55(3):181-184. doi: 10.1016/j.patol.2020.11.001. Epub 2020 Dec 30.
Circumscribed palmar or plantar hypokeratosis (CPH) is a depressed, well-delimited, erythematous lesion usually found in the thenar and hypothenar regions of the palms or the soles, predominately in women. It was first described by Pérez et al. in 2002 as a benign entity of unknown origin. Histologically, the depressed area corresponds to a thinning of the stratum corneum. It is a well-demarcated lesion with a sharp stair in the stratum corneum between normal and involved skin and the affected corneocytes are more eosinophilic than normal. We present two new cases of CPH, both occurring in females and in the hand, one of which was located in the thenar region and the other in the finger. We discuss the histopathological and dermatoscopical findings.
局限性掌跖角化不全（CPH）是一种凹陷性、边界清晰的红斑性损害，通常见于手掌或足底的大鱼际和小鱼际区域，女性多见。它于2002年由佩雷斯等人首次描述为一种病因不明的良性病变。组织学上，凹陷区域对应角质层变薄。这是一种边界清晰的损害，在正常皮肤和受累皮肤之间的角质层有明显的阶梯状变化，且受累角质形成细胞比正常细胞更嗜酸性。我们报告两例新的CPH病例，均发生于女性手部，其中一例位于大鱼际区域，另一例位于手指。我们讨论了组织病理学和皮肤镜检查结果。
