Shetty Pushparaja H, Naik Ravishankar K, Saroja Ao, Punith K
Department of Neurology, M S Ramaiah Hospital, MSRIT Post, New BEL Road, Bangalore, India.
J Neurosci Rural Pract. 2011 Jan;2(1):33-8. doi: 10.4103/0976-3147.80092.
People with epilepsy have impairment in their quality of life (QOL) due to effect of epilepsy on various aspects of their life and the medication effects. Systematic studies on QOL in epilepsy from developing countries are sparse.
To assess the QOL in people with epilepsy and to evaluate various factors affecting the QOL in them.
People with generalized and partial epilepsy on medication aged more than 18 years were included in the study. The QOL was assessed with QOLIE-89 instrument. Statistical significance was evaluated by the use of Chi-square test and one-way analysis of variance (ANOVA).
Sixty people with epilepsy were studied among whom the older patients had lower overall QOL scores compared to younger patients. Female patients had lower scores compared to males. Married people had lower quality of health score. Patients with simple partial seizures had lowest overall QOL mean score. There was reduction in the overall QOLIE scores with increasing duration of the epilepsy. Patients who had their last seizure within 10 months prior to evaluation had lower mean overall scores.
QOL was impaired in people with epilepsy with increased impairment in women, older patients, simple partial seizures, and those with recent seizure.
癫痫患者的生活质量（QOL）受到癫痫对其生活各个方面的影响以及药物作用的损害。来自发展中国家的关于癫痫患者生活质量的系统性研究较少。
评估癫痫患者的生活质量，并评估影响他们生活质量的各种因素。
研究纳入年龄超过18岁、正在接受药物治疗的全身性和部分性癫痫患者。使用生活质量癫痫问卷-89（QOLIE-89）工具评估生活质量。采用卡方检验和单因素方差分析（ANOVA）评估统计学意义。
对60例癫痫患者进行了研究，其中老年患者的总体生活质量得分低于年轻患者。女性患者的得分低于男性。已婚者的健康质量得分较低。单纯部分性发作患者的总体生活质量平均得分最低。随着癫痫病程的延长，QOLIE总体得分降低。在评估前10个月内有过最后一次发作的患者平均总体得分较低。
癫痫患者的生活质量受损，女性、老年患者、单纯部分性发作患者以及近期发作的患者受损程度更高。
