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[不宁腿综合征与夜间腿痛:鉴别诊断与治疗]

[Restless legs syndrome and nocturnal leg pain : Differential diagnosis and treatment].

作者信息

Hornyak M, Stiasny-Kolster K, Evers S, Happe S

机构信息

Interdisziplinäres Schmerzzentrum, Universitätsklinikum Freiburg, Breisacher Str. 64, 79106, Freiburg, Deutschland.

出版信息

Schmerz. 2011 Sep;25(5):544-51. doi: 10.1007/s00482-011-1074-8.

DOI:10.1007/s00482-011-1074-8
PMID:21717211
Abstract

Pain in the legs belongs to the five most frequent regional pain symptoms. Restless legs syndrome (RLS) presents a particular differential diagnosis for pain in the legs, which is characterized by a nocturnal urge to move the legs often associated with painful sensations in the legs. It is one of the most common neurological disorders and probably the leading cause of nocturnal pain in the legs. In this overview, the diagnosis and therapy of RLS as well as aspects of pain therapy of the disorder are presented. In addition, the differential diagnoses for exclusion of other specific causes of nocturnal pain in the legs are discussed.

摘要

腿部疼痛属于五大常见的局部疼痛症状之一。不安腿综合征(RLS)是腿部疼痛的一种特殊鉴别诊断,其特征是夜间有移动腿部的冲动,常伴有腿部疼痛感。它是最常见的神经系统疾病之一,可能是导致夜间腿部疼痛的主要原因。在本综述中,介绍了不安腿综合征的诊断和治疗以及该疾病疼痛治疗的相关方面。此外,还讨论了用于排除腿部夜间疼痛其他特定原因的鉴别诊断。

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引用本文的文献

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本文引用的文献

1
Poor effect of guideline based treatment of restless legs syndrome in clinical practice.临床实践中基于指南的不安腿综合征治疗效果不佳。
J Neurol Neurosurg Psychiatry. 2010 Dec;81(12):1390-5. doi: 10.1136/jnnp.2010.211417. Epub 2010 Sep 30.
2
The four diagnostic criteria for Restless Legs Syndrome are unable to exclude confounding conditions ("mimics").不安腿综合征的四项诊断标准无法排除混杂条件(“类似病症”)。
Sleep Med. 2009 Oct;10(9):976-81. doi: 10.1016/j.sleep.2008.09.015. Epub 2009 Jan 29.
3
Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study.
内源性阿片系统在不宁腿综合征中起作用吗?一项尸检初步研究。
J Neurol Sci. 2009 Apr 15;279(1-2):62-5. doi: 10.1016/j.jns.2008.12.022. Epub 2009 Jan 23.
4
Restless legs syndrome is common among female patients with fibromyalgia.不安腿综合征在纤维肌痛女性患者中很常见。
Eur Neurol. 2009;61(2):107-11. doi: 10.1159/000180313. Epub 2008 Dec 9.
5
Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice.不宁腿综合征的治疗:基于证据的综述及对临床实践的启示
Mov Disord. 2008 Dec 15;23(16):2267-302. doi: 10.1002/mds.22254.
6
Treatment wish of individuals with known and unknown restless legs syndrome in the community.社区中已知和未知不安腿综合征患者的治疗意愿。
J Neurol. 2008 Sep;255(9):1365-71. doi: 10.1007/s00415-008-0922-7. Epub 2008 Jun 27.
7
Assessing health-related quality of life in patients with restless legs syndrome.评估不宁腿综合征患者与健康相关的生活质量。
Sleep Med. 2009 Mar;10(3):295-305. doi: 10.1016/j.sleep.2008.01.002. Epub 2008 Mar 24.
8
Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community.不宁腿综合征与社区中的DSM-IV重度抑郁症和惊恐障碍有关。
J Neuropsychiatry Clin Neurosci. 2008 Winter;20(1):101-5. doi: 10.1176/jnp.2008.20.1.101.
9
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.不宁腿综合征的全基因组关联研究确定了三个基因组区域中的常见变异。
Nat Genet. 2007 Aug;39(8):1000-6. doi: 10.1038/ng2099. Epub 2007 Jul 18.
10
Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute.不宁腿综合征多巴胺能增强的诊断标准:马克斯·普朗克研究所世界睡眠医学协会-国际不宁腿综合征研究小组共识会议报告
Sleep Med. 2007 Aug;8(5):520-30. doi: 10.1016/j.sleep.2007.03.022. Epub 2007 Jun 1.