Department of Zoology, University of Delhi, Delhi, India.
J Gerontol A Biol Sci Med Sci. 2011 Sep;66(9):965-71. doi: 10.1093/gerona/glr103. Epub 2011 Jun 30.
Longevity extension in Drosophila melanogaster by feeding diet supplemented with chemicals throughout adulthood can cause harmful side effects. We tested the effect of larval diet supplementation with five different concentrations of resveratrol and one concentration of Aloe vera extract on the adult longevity of short-lived D melanogaster populations. Resveratrol and A vera extract supplementation of larval diet extended adult longevity in both the male and female flies without reducing fecundity but by efficient reactive oxygen species scavenging through increased antioxidant enzymes activity and better neuroprotection as indicated by increased locomotor activity in adult males.
通过在成年期喂食补充化学物质的饮食来延长黑腹果蝇的寿命可能会产生有害的副作用。我们测试了用五种不同浓度的白藜芦醇和一种浓度的芦荟提取物喂养幼虫饮食对短寿命黑腹果蝇种群成虫寿命的影响。白藜芦醇和芦荟提取物补充幼虫饮食延长了雌雄蝇的成虫寿命，而不会降低繁殖力，但通过增加抗氧化酶活性来有效清除活性氧物质，并通过增加雄性成虫的运动活性来更好地保护神经，从而实现这一目标。
