Burk Thomas F, Horvai Andrew E, Gottschalk Alexander R, Leong Stanley P L, Kashani-Sabet Mohammed, Goldsby Robert E, Law Jason, O'Donnell Richard J
Department of Orthopaedic Surgery, University of California, San Francisco, USA.
Am J Orthop (Belle Mead NJ). 2010 Dec;39(12):582-6.
The incidence of melanoma in US adults is approximately 1.5 per million, with 2% to 5% of patients developing metastatic disease. In children, melanoma is distinctly uncommon, and metastatic disease occurs even more seldom. This case report, the first of a patellar lesion as the initial presentation of metastatic melanoma in a pediatric patient, highlights use of patellectomy and intraoperative radiation therapy in obtaining palliative local control while avoiding periarticular functional morbidity.
美国成年人黑色素瘤的发病率约为百万分之1.5,其中2%至5%的患者会发展为转移性疾病。在儿童中,黑色素瘤明显不常见,转移性疾病更是罕见。本病例报告是首例以髌骨病变为小儿转移性黑色素瘤初始表现的病例,强调了采用髌骨切除术和术中放射治疗来实现姑息性局部控制,同时避免关节周围功能障碍。