College of Life Science, Hunan University of Arts and Science, Changde, Hunan 415000, China.
Am J Chin Med. 2011;39(4):719-26. doi: 10.1142/S0192415X11009159.
Asparagus cochinchinensis is a traditional Chinese medicine used for treating lung and spleen-related diseases. In this study, we compared the medicinal effects of A. cochinchinensis root and stem extracts on the activity of superoxide dismutase (SOD), the content of malonaldehyde (MDA) and total protein content in the brain, liver and plasma of mice. Polysaccharides and aqueous extracts of the roots significantly increased the spleen index and the SOD activity but reduced the MDA content and slowed down the aging process. In contrast, feeding with the stem extracts significantly reduced the SOD activity and increased the MDA accumulation in the brain and liver of mice, suggesting that the stem extracts may not be appropriate for treating aging-related diseases.
天门冬是一种传统的中药，用于治疗肺和脾相关疾病。在这项研究中，我们比较了天门冬根和茎提取物对小鼠大脑、肝脏和血浆中超氧化物歧化酶（SOD）活性、丙二醛（MDA）含量和总蛋白含量的影响。多糖和根的水提物显著增加了脾指数和 SOD 活性，降低了 MDA 含量，减缓了衰老过程。相比之下，喂食茎提取物显著降低了小鼠大脑和肝脏中的 SOD 活性，并增加了 MDA 的积累，这表明茎提取物可能不适合治疗与衰老相关的疾病。
