牛蒡根抗衰老作用的实验研究
An experimental research into the anti-aging effects of Radix Arctii Lappae.
作者信息
Liu Shumin, Li Yujie, Li Shulian, Luo Mingmei, Liu Xinlin
机构信息
Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
出版信息
J Tradit Chin Med. 2005 Dec;25(4):296-9.
PURPOSE
To delve into the anti-aging effects and mechanism of Niubanggen (Radix Arctii Lappae).
METHOD
The activity of SOD and the content of MDA and lipofuscin in the tissues of the liver, brain and blood serum of the lab rats were observed 30 days after they had been fed with the Niubanggen decoction.
RESULT
The activity of SOD in the liver tissue and blood serum of the decoction-fed lab rats was improved dramatically (P<0.05 or P<0.01), the content of MDA in the brain tissue and blood serum lowered obviously (P<0.05 or P<0.01), and the content of lipofuscin dropped distinctly (P<0.01).
CONCLUSION
The mechanism of the anti-aging effects of the Niubanggen is mainly obtained by raising the activity of SOD and reducing the contents of MDA and lipofuscin.
目的
探讨牛蒡根的抗衰老作用及机制。
方法
给实验大鼠喂服牛蒡根水煎剂30天后，观察其肝、脑及血清组织中SOD活性、MDA及脂褐素含量。
结果
喂服水煎剂的实验大鼠肝组织及血清中SOD活性显著提高（P<0.05或P<0.01），脑组织及血清中MDA含量明显降低（P<0.05或P<0.01），脂褐素含量显著下降（P<0.01）。
结论
牛蒡根抗衰老作用机制主要是通过提高SOD活性、降低MDA及脂褐素含量来实现。
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