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蔬菜及其生物活性化合物作为抗衰老药物。

Vegetables and Their Bioactive Compounds as Anti-Aging Drugs.

机构信息

Laboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences, University Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.

Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10106, Morocco.

出版信息

Molecules. 2022 Apr 2;27(7):2316. doi: 10.3390/molecules27072316.

Abstract

Aging is a continuous process over time that is mainly related to natural alterations in mechanical-biological processes. This phenomenon is due to several factors, including the time and energy of biological processes. Aging can be attributed to biological factors such as oxidative stress, cell longevity, and stem cell senescence. Currently, aging is associated with several diseases, such as neurodegenerative diseases, cancer, and other diseases related to oxidative stress. In addition, certain natural molecules, including those derived from vegetables, have shown the ability to delay the aging process. Their effects are linked to different mechanisms of action, such as tissue regeneration and the activation of longevity and anti-senescence genes. The present work discusses the impact of vegetables, and bioactive compounds isolated from vegetables, against the physiological and pathological aging process and accompanying human diseases.

摘要

衰老是一个随时间持续发生的过程,主要与机械生物学过程的自然改变有关。这种现象归因于多个因素,包括生物过程的时间和能量。衰老是由生物因素引起的,例如氧化应激、细胞寿命和干细胞衰老。目前,衰老与几种疾病有关,如神经退行性疾病、癌症和其他与氧化应激有关的疾病。此外,某些天然分子,包括来自蔬菜的分子,已显示出延缓衰老过程的能力。它们的作用与不同的作用机制有关,例如组织再生以及长寿和抗衰老基因的激活。本工作讨论了蔬菜及其从蔬菜中分离得到的生物活性化合物对生理和病理性衰老过程以及伴随的人类疾病的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b014/9000296/662cd0229759/molecules-27-02316-g001.jpg

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