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饮食、体重与结直肠癌:斯德哥尔摩的一项病例对照研究。

Diet, body mass and colorectal cancer: a case-referent study in Stockholm.

作者信息

Gerhardsson de Verdier M, Hagman U, Steineck G, Rieger A, Norell S E

机构信息

Department of Epidemiology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Int J Cancer. 1990 Nov 15;46(5):832-8. doi: 10.1002/ijc.2910460514.

DOI:10.1002/ijc.2910460514
PMID:2172171
Abstract

A population-based case-referent study on diet (total energy, protein, fat, dietary fiber), body mass and colorectal cancer was performed in Stockholm in 1986-1988. The study included 1,081 subjects. The relative risks (RR, with a 95% confidence interval, highest versus lowest quintile) for colon cancer were as follows: total energy (1.7, 1.0-3.0), protein (2.4, 1.5-4.0), total fat (2.2, 1.3-3.6), dietary fiber for men (0.5, 0.2-1.1), dietary fiber for women (1.2, 0.7-2.3) and body mass (2.0, 1.3-3.1). The relative risks for rectal cancer were: total energy (2.4, 1.2-4.7), protein (3.6, 2.0-6.4), total fat (2.5, 1.4-4.6), dietary fiber (0.5, 0.3-0.9), body mass for men (1.7, 0.7-4.0), and body mass for women (1.0, 0.5-1.9). Adjustment for physical activity, body mass (in the diet analysis), the above-mentioned dietary factors (in the body mass analysis), and browned meat surface had little or no influence on the results.

摘要

1986年至1988年在斯德哥尔摩开展了一项基于人群的病例对照研究,探讨饮食(总能量、蛋白质、脂肪、膳食纤维)、体重与结直肠癌之间的关系。该研究纳入了1081名受试者。结肠癌的相对风险(RR,95%置信区间,最高五分位数与最低五分位数相比)如下:总能量(1.7,1.0 - 3.0)、蛋白质(2.4,1.5 - 4.0)、总脂肪(2.2,1.3 - 3.6)、男性膳食纤维(0.5,0.2 - 1.1)、女性膳食纤维(1.2,0.7 - 2.3)以及体重(2.0,1.3 - 3.1)。直肠癌的相对风险为:总能量(2.4,1.2 - 4.7)、蛋白质(3.6,2.0 - 6.4)、总脂肪(2.5,1.4 - 4.6)、膳食纤维(0.5,0.3 - 0.9)、男性体重(1.7,0.7 - 4.0)以及女性体重(1.0,0.5 - 1.9)。对体力活动、体重(在饮食分析中)、上述饮食因素(在体重分析中)以及肉类表面褐变进行校正后,对结果影响很小或没有影响。

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