Stockholm Centre for Healthcare Ethics, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Genome Med. 2011 Jun 28;3(6):41. doi: 10.1186/gm257.
In a time when the challenge of people being over-researched and experiencing research fatigue is increasingly discussed, low participation rates and potential sample biases are a growing concern in genetic research. In a recent study assessing factors relevant to successful recruitment of patients with myocardial infarction to a genetic study, enrollment site was identified as the most important factor associated with patient participation, whereas patient-level factors such as race, gender and education played a limited or no role. These results underline the importance of appropriate recruitment routines at enrollment sites in order to reach high levels of participation in genetic research.See research article: http://genomemedicine.com/content/3/6/39.
在人们过度研究和经历研究疲劳的挑战日益受到讨论的时代，低参与率和潜在的样本偏差是遗传研究中越来越令人关注的问题。在最近一项评估与成功招募心肌梗死患者参加遗传研究相关因素的研究中，入组地点被确定为与患者参与度最相关的最重要因素，而患者层面的因素，如种族、性别和教育程度，则作用有限或没有作用。这些结果强调了在入组地点制定适当的招募程序以达到遗传研究高参与率的重要性。参见研究文章：http://genomemedicine.com/content/3/6/39.
