Division of Cardiology, Department of Medicine, Emory University School of Medicine and Grady Memorial Hospital, Atlanta, Georgia, USA.
Rev Esp Cardiol. 2011 Aug;64(8):697-712. doi: 10.1016/j.recesp.2011.05.001. Epub 2011 Jul 1.
The aging of the population worldwide will result in increasing numbers of elderly patients, among whom heart disease is the leading cause of death. Changes in cardiovascular physiology with normal aging and prevalent comorbidities result in differences in the effects of common cardiac problems as well as the response to their treatments. Patient-centered goals of care such as maintenance of independence and reduction of symptoms may be preferred over increased longevity. New less-invasive treatments are likely to improve outcomes in elderly patients who previously have been considered at prohibitive risk for traditional procedures. Clinical trials enrolling elderly patients are limited and recommendations for management from younger patients frequently lack evidence-based support in patients aged >75 years.
全球人口老龄化将导致老年患者人数增加，其中心脏病是主要死因。随着年龄的增长，心血管生理学发生变化，再加上常见的合并症，导致常见心脏问题的影响以及对其治疗的反应也有所不同。以患者为中心的护理目标，如保持独立性和减少症状，可能比延长寿命更为重要。新的微创治疗方法可能会改善以前被认为传统手术风险过高的老年患者的预后。招募老年患者的临床试验有限，而对于年龄>75 岁的患者，来自年轻患者的管理建议通常缺乏基于证据的支持。
