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应用 k-t BLAST 加速的相位对比磁共振测量主动脉瓣狭窄患者的血流和峰值速度。

Flow and peak velocity measurements in patients with aortic valve stenosis using phase contrast MR accelerated with k-t BLAST.

机构信息

Department of Medical Physics, Örebro University Hospital, S-70185 Örebro, Sweden.

出版信息

Eur J Radiol. 2012 Sep;81(9):2203-7. doi: 10.1016/j.ejrad.2011.06.034. Epub 2011 Jul 2.

Abstract

OBJECTIVE

To investigate the accuracy of velocity measurements in patients with aortic valve stenosis using phase contrast (PC) imaging accelerated with SENSE (Sensitivity Encoding) and k-t BLAST (Broad-use Linear Acquisition Speed-up Technique).

METHODS

Accelerated quantitative breath hold PC measurements, using SENSE and k-t BLAST, were performed in twelve patients whose aortic valve stenosis had been initially diagnosed using echocardiography. Stroke volume (SV) and peak velocity measurements were performed on each subject in three adjacent slices using both accelerating methods.

RESULTS

The peak velocities measured with PC MRI using SENSE were -8.0±9.5% lower (p<0.01) compared to the peak velocities measured with k-t BLAST and the correlation was r=0.83. The stroke volumes when using SENSE were slightly higher 0.4±17.1 ml compared to the SV obtained using k-t BLAST but the difference was not significant (p>0.05).

CONCLUSIONS

In this study higher peak velocities were measured in patients with aortic stenosis when combining k-t BLAST with PC MRI compared to PC MRI using SENSE. A probable explanation of this difference is the higher temporal resolution achieved in the k-t BLAST measurement. There was, however, no significant difference between calculated SV based on PC MRI using SENSE and k-t BLAST, respectively.

摘要

目的

利用相位对比(PC)成像加速敏感度编码(SENSE)和 k-t BLAST(宽用途线性加速采集技术),研究主动脉瓣狭窄患者速度测量的准确性。

方法

对经超声心动图初步诊断为主动脉瓣狭窄的 12 例患者进行加速定量屏气 PC 测量,使用 SENSE 和 k-t BLAST。两种加速方法分别对每位患者的三个相邻层面进行测量,得出心搏量(SV)和峰值速度。

结果

与 k-t BLAST 相比,使用 SENSE 的 PC MRI 测量的峰值速度低了-8.0±9.5%(p<0.01),相关性为 r=0.83。使用 SENSE 的 SV 比使用 k-t BLAST 略高 0.4±17.1 ml,但差异无统计学意义(p>0.05)。

结论

本研究中,与 SENSE 联合 k-t BLAST 的 PC MRI 相比,在主动脉瓣狭窄患者中测量到的峰值速度更高。这种差异的可能解释是 k-t BLAST 测量中实现了更高的时间分辨率。然而,基于 SENSE 和 k-t BLAST 的 PC MRI 计算的 SV 之间没有显著差异。

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