Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Andrologia. 2012 May;44 Suppl 1:323-8. doi: 10.1111/j.1439-0272.2011.01184.x. Epub 2011 Jul 6.
This study aimed to investigate the effects of Kaempferia parviflora extract (KD) and exercise training on reproductive function in male rats. Sexually mature males were assigned to four groups: control, KD70 (received 70 mg kg(-1) day(-1) for 4 weeks), Ex (exercise training for 4 weeks), Ex + KD70 (exercise training with KD 70 mg kg(-1) day(-1)). At the end of treatment regimes, sexual behaviours including mount latency (ML), mount frequency (MF), ejaculation latency (EL), post-ejaculation latency (PEL), number of mount within 30 min (MF(30)) and number of ejaculation (NEL) were assessed by a video camera, and fertility was tested by natural mating. Results showed that KD had no effect on the weights of reproductive organs, liver, kidneys and levator ani muscle. On the other hand, the weights of epididymis, seminal vesicles, prostate gland and levator ani muscle were significantly increased in the Ex and Ex+KD70 groups. ML and EL were shortened in all treatment groups, but PEL was decreased only in KP70 group. Only Ex and Ex + KD70 groups exhibited lower MF and higher NEL whilst MF(30) were not changed in all groups. None of the treatments altered male fertility. It is concluded that KD enhanced sexual motivation whereas exercise training promoted both sexual motivation and performance.
本研究旨在探讨山奈酚提取物 (KD) 和运动训练对雄性大鼠生殖功能的影响。将性成熟雄性大鼠分为四组：对照组、KD70 组（接受 70mg/kg/天的 KD 治疗 4 周）、运动组（运动训练 4 周）和运动+KD70 组（运动训练并给予 70mg/kg/天的 KD）。在治疗结束时，使用摄像机评估性行为，包括交配潜伏期 (ML)、交配频率 (MF)、射精潜伏期 (EL)、射精后潜伏期 (PEL)、30 分钟内交配次数 (MF(30)) 和射精次数 (NEL)，并通过自然交配测试生育能力。结果表明，KD 对生殖器官、肝脏、肾脏和肛提肌的重量没有影响。另一方面，运动组和运动+KD70 组的附睾、精囊、前列腺和肛提肌重量显著增加。所有治疗组的 ML 和 EL 缩短，但只有 KD70 组的 PEL 降低。只有运动组和运动+KD70 组的 MF 和 NEL 降低，而所有组的 MF(30)均无变化。这些治疗均未改变雄性生育能力。结论是，KD 增强了性动机，而运动训练则促进了性动机和性表现。
