Saokaew Surasak, Wilairat Preyanate, Raktanyakan Paranya, Dilokthornsakul Piyameth, Dhippayom Teerapon, Kongkaew Chuenjid, Sruamsiri Rosarin, Chuthaputti Anchalee, Chaiyakunapruk Nathorn
1 University of Phayao, Phayao, Thailand.
2 Monash University Malaysia, Kuala Lumpur, Malaysia.
J Evid Based Complementary Altern Med. 2017 Jul;22(3):413-428. doi: 10.1177/2156587216669628. Epub 2016 Sep 30.
Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.
小花山柰(Krachaidum)是姜科的一种药用植物。其根茎作为民间药物已使用了数百年。多项关于Krachaidum的药理学研究声称其对各种疾病有益。因此,本研究旨在系统检索和总结Krachaidum在所有已确定适应症方面的临床证据。在检索到的683条记录中,纳入了7项研究。从目前的临床试验来看,Krachaidum显示出积极效果,但由于纳入的研究规模较小,结论仍不明确。尽管结果发现Krachaidum显著提高了握力并增强了性刺激,但这些分别仅基于2项研究和1项研究。关于有害影响,我们发现即使使用每天1.35克的Krachaidum,也没有不良事件报告。因此,需要对Krachaidum的安全性和有效性结果进行进一步研究。