• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小花山柰的临床效果:一项系统评价

Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review.

作者信息

Saokaew Surasak, Wilairat Preyanate, Raktanyakan Paranya, Dilokthornsakul Piyameth, Dhippayom Teerapon, Kongkaew Chuenjid, Sruamsiri Rosarin, Chuthaputti Anchalee, Chaiyakunapruk Nathorn

机构信息

1 University of Phayao, Phayao, Thailand.

2 Monash University Malaysia, Kuala Lumpur, Malaysia.

出版信息

J Evid Based Complementary Altern Med. 2017 Jul;22(3):413-428. doi: 10.1177/2156587216669628. Epub 2016 Sep 30.

DOI:10.1177/2156587216669628
PMID:27694558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5871153/
Abstract

Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.

摘要

小花山柰(Krachaidum)是姜科的一种药用植物。其根茎作为民间药物已使用了数百年。多项关于Krachaidum的药理学研究声称其对各种疾病有益。因此,本研究旨在系统检索和总结Krachaidum在所有已确定适应症方面的临床证据。在检索到的683条记录中,纳入了7项研究。从目前的临床试验来看,Krachaidum显示出积极效果,但由于纳入的研究规模较小,结论仍不明确。尽管结果发现Krachaidum显著提高了握力并增强了性刺激,但这些分别仅基于2项研究和1项研究。关于有害影响,我们发现即使使用每天1.35克的Krachaidum,也没有不良事件报告。因此,需要对Krachaidum的安全性和有效性结果进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/fc43fae44e3d/10.1177_2156587216669628-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/78c234ae9ef1/10.1177_2156587216669628-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/eb85beae8e72/10.1177_2156587216669628-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/fc43fae44e3d/10.1177_2156587216669628-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/78c234ae9ef1/10.1177_2156587216669628-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/eb85beae8e72/10.1177_2156587216669628-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d0/5871153/fc43fae44e3d/10.1177_2156587216669628-fig3.jpg

相似文献

1
Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review.小花山柰的临床效果:一项系统评价
J Evid Based Complementary Altern Med. 2017 Jul;22(3):413-428. doi: 10.1177/2156587216669628. Epub 2016 Sep 30.
2
Kaempferia parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low affinity PDE5 inhibitors.卡宴小姜,一种用于传统医学以提高性表现的植物,含有大量低亲和力 PDE5 抑制剂。
J Ethnopharmacol. 2011 Oct 11;137(3):1437-41. doi: 10.1016/j.jep.2011.08.025. Epub 2011 Aug 30.
3
Kaempferia parviflora ethanol extract improves self-assessed sexual health in men: a pilot study.山柰乙醇提取物可改善男性自评的性健康:一项初步研究。
J Integr Med. 2018 Jul;16(4):249-254. doi: 10.1016/j.joim.2018.05.005. Epub 2018 May 26.
4
Effect of Kaempferia parviflora Extract on Physical Fitness of Soccer Players: A Randomized Double-Blind Placebo-Controlled Trial.小花山柰提取物对足球运动员体能的影响:一项随机双盲安慰剂对照试验
Med Sci Monit Basic Res. 2015 May 6;21:100-8. doi: 10.12659/MSMBR.894301.
5
Modulatory effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.山奈提取物对小鼠肝细胞色素 P450 酶的调节作用。
J Ethnopharmacol. 2012 Jun 14;141(3):831-9. doi: 10.1016/j.jep.2012.03.023. Epub 2012 Mar 28.
6
Effects of Kaempferia parviflora extracts on reproductive parameters and spermatic blood flow in male rats.小花山柰提取物对雄性大鼠生殖参数和精索血流的影响。
Reproduction. 2008 Oct;136(4):515-22. doi: 10.1530/REP-08-0069. Epub 2008 Jul 9.
7
No effect of acute ingestion of Thai ginseng (Kaempferia parviflora) on sprint and endurance exercise performance in humans.泰国人参(Kaempferia parviflora)急性摄入对人体短跑和耐力运动表现无影响。
J Sports Sci. 2010 Sep;28(11):1243-50. doi: 10.1080/02640414.2010.506221.
8
Effect of Kaempferia parviflora Wall. ex. Baker on sexual activity of male rats and its toxicity.小花山柰(Kaempferia parviflora Wall. ex. Baker)对雄性大鼠性行为的影响及其毒性
Southeast Asian J Trop Med Public Health. 2006;37 Suppl 3:210-5.
9
Effects of Kaempferia parviflora rhizomes dichloromethane extract on vascular functions in middle-aged male rat.小花山柰根茎二氯甲烷提取物对中年雄性大鼠血管功能的影响
J Ethnopharmacol. 2014 Oct 28;156:162-74. doi: 10.1016/j.jep.2014.08.020. Epub 2014 Aug 27.
10
Effects of Kaempferia parviflora extracts and their flavone constituents on P-glycoprotein function.小花山柰提取物及其黄酮成分对P-糖蛋白功能的影响。
J Pharm Sci. 2007 Jan;96(1):223-33. doi: 10.1002/jps.20769.

引用本文的文献

1
Effects of Thai Extract on Human Gingival Fibroblasts: An Study of Wound Healing.泰国提取物对人牙龈成纤维细胞的影响:一项伤口愈合研究。
J Int Soc Prev Community Dent. 2025 Apr 30;15(2):126-133. doi: 10.4103/jispcd.jispcd_214_24. eCollection 2025 Mar-Apr.
2
Kaempferia parviflora extract and its methoxyflavones as potential anti-Alzheimer assessing in vitro, integrated computational approach, and in vivo impact on behaviour in scopolamine-induced amnesic mice.山柰提取物及其甲氧基黄酮作为潜在抗阿尔茨海默病药物的体外评估、综合计算方法以及对东莨菪碱诱导的记忆缺失小鼠行为的体内影响
PLoS One. 2025 Mar 10;20(3):e0316888. doi: 10.1371/journal.pone.0316888. eCollection 2025.
3

本文引用的文献

1
Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells.山柰提取物对人脐静脉内皮细胞单核细胞黏附及细胞活性氧生成的抑制作用。
Eur J Nutr. 2017 Apr;56(3):949-964. doi: 10.1007/s00394-015-1141-5. Epub 2015 Dec 24.
2
Kaempferia parviflora extract increases whole-body energy expenditure in humans: roles of brown adipose tissue.小花山柰提取物可增加人体全身能量消耗:棕色脂肪组织的作用
J Nutr Sci Vitaminol (Tokyo). 2015;61(1):79-83. doi: 10.3177/jnsv.61.79.
3
Effect of Kaempferia parviflora Extract on Physical Fitness of Soccer Players: A Randomized Double-Blind Placebo-Controlled Trial.
8-Week Extract Administration Improves Submaximal Exercise Capacity in Mice by Enhancing Skeletal Muscle Antioxidant Gene Expression and Plasma Antioxidant Capacity.
8周提取物给药通过增强骨骼肌抗氧化基因表达和血浆抗氧化能力提高小鼠亚极量运动能力。
Antioxidants (Basel). 2024 Sep 23;13(9):1147. doi: 10.3390/antiox13091147.
4
Skin Rejuvenation Efficacy and Safety Evaluation of Standardized Extract (BG100) in Human 3D Skin Models and Clinical Trial.标准化提取物(BG100)在人体 3D 皮肤模型中的皮肤焕肤功效和安全性评价及临床试验。
Biomolecules. 2024 Jun 29;14(7):776. doi: 10.3390/biom14070776.
5
A Functional Drink Containing Extract Increases Cardiorespiratory Fitness and Physical Flexibility in Adult Volunteers.一种含有提取物的功能性饮料可提高成年志愿者的心肺功能和身体柔韧性。
Foods. 2023 Sep 13;12(18):3411. doi: 10.3390/foods12183411.
6
Kaempferia parviflora rhizome extract exerts anti-obesity effect in high-fat diet-induced obese C57BL/6N mice.小花山柰根茎提取物对高脂饮食诱导的肥胖C57BL/6N小鼠具有抗肥胖作用。
Food Nutr Res. 2023 Aug 23;67. doi: 10.29219/fnr.v67.9413. eCollection 2023.
7
The potential of traditional herbal active ingredients in the treatment of sarcopenia animal models: focus on therapeutic effects and mechanisms.传统草药活性成分在治疗肌肉减少症动物模型中的潜力:聚焦于治疗效果和机制
Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec;396(12):3483-3501. doi: 10.1007/s00210-023-02639-7. Epub 2023 Aug 1.
8
Antiobesity effect of accompanied by inhibition of lipogenesis and stimulation of lipolysis.伴随着脂肪生成抑制和脂肪分解刺激的抗肥胖作用。 (原英文句子表述不太完整规范,翻译出来的中文也稍显生硬,但根据要求严格按原文翻译)
Food Nutr Res. 2023 Jul 3;67. doi: 10.29219/fnr.v67.9374. eCollection 2023.
9
The industrially important genus : An ethnopharmacological review.具有工业重要性的属:民族药理学综述。
Front Pharmacol. 2023 Feb 27;14:1099523. doi: 10.3389/fphar.2023.1099523. eCollection 2023.
10
Methoxyflavones from Black Ginger ( Wall. ex Baker) and their Inhibitory Effect on Melanogenesis in B16F10 Mouse Melanoma Cells.黑姜(Wall. ex Baker)中的甲氧基黄酮及其对B16F10小鼠黑色素瘤细胞黑色素生成的抑制作用。
Plants (Basel). 2023 Mar 5;12(5):1183. doi: 10.3390/plants12051183.
小花山柰提取物对足球运动员体能的影响:一项随机双盲安慰剂对照试验
Med Sci Monit Basic Res. 2015 May 6;21:100-8. doi: 10.12659/MSMBR.894301.
4
Kaempferia parviflora extract increases energy consumption through activation of BAT in mice.山奈提取物通过激活小鼠的 BAT 增加能量消耗。
Food Sci Nutr. 2014 Nov;2(6):634-7. doi: 10.1002/fsn3.144. Epub 2014 Jul 15.
5
Identification and evaluation of anti-inflammatory compounds from Kaempferia parviflora.从小花山柰中鉴定和评估抗炎化合物。
Biosci Biotechnol Biochem. 2014;78(5):851-60. doi: 10.1080/09168451.2014.905177. Epub 2014 May 15.
6
Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora.从山奈中分离得到的多甲氧基黄酮抑制脂肪细胞肥大。
Phytomedicine. 2014 May 15;21(6):800-6. doi: 10.1016/j.phymed.2014.01.014. Epub 2014 Mar 11.
7
Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers.8 周食用小花山奈对健康老年志愿者健康相关体适能和氧化状态的正向调节作用。
Evid Based Complement Alternat Med. 2012;2012:732816. doi: 10.1155/2012/732816. Epub 2012 Jul 31.
8
Kaempferia parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low affinity PDE5 inhibitors.卡宴小姜,一种用于传统医学以提高性表现的植物,含有大量低亲和力 PDE5 抑制剂。
J Ethnopharmacol. 2011 Oct 11;137(3):1437-41. doi: 10.1016/j.jep.2011.08.025. Epub 2011 Aug 30.
9
Enhancement of aphrodisiac activity in male rats by ethanol extract of Kaempferia parviflora and exercise training.乙醇提取物联合运动训练增强雄性大鼠壮阳活性。
Andrologia. 2012 May;44 Suppl 1:323-8. doi: 10.1111/j.1439-0272.2011.01184.x. Epub 2011 Jul 6.
10
The ethanolic extract of Kaempferia parviflora reduces ischaemic injury in rat isolated hearts.山柰酚素提取物可减少大鼠离体心脏的缺血性损伤。
J Ethnopharmacol. 2011 Sep 1;137(1):184-91. doi: 10.1016/j.jep.2011.05.004. Epub 2011 May 10.