Meštrović T, Sviben M, Vilibić-Čavlek T, Ljubin-Sternak S, Tabain I, Mlinarić-Galinović G
Polyclinic for Medical Microbiology and Parasitology Dr. Zora Profozic, Zagreb, Croatia.
J Helminthol. 2012 Sep;86(3):259-62. doi: 10.1017/S0022149X11000253. Epub 2011 Jun 1.
Epilepsy is one of the most common neurological disorders, while neurocysticercosis caused by Taenia solium infection of the central nervous system currently represents the leading cause of secondary epilepsy in Central and South America, East and South Asia, and sub-Saharan Africa. As a result of increased migration from these endemic regions, neurocysticercosis and subsequent epilepsy are becoming a growing public health problem in developed countries as well. In order to determine the prevalence of T. solium infection in patients with epilepsy in Croatia, a retrospective serological study was conducted. A total of 770 serum samples were tested for the presence of T. solium IgG antibodies using a commercial qualitative enzyme immunoassay. The Western blot technique was used as a confirmatory test for the diagnosis. The overall seroprevalence rate of T. solium infection in patients with clinically proven epilepsy was 1.5%. Although the results have shown that infection with this tapeworm is rare in Croatia, this study hopes to increase awareness about the importance of preventive measures and benefits of accurate and timely diagnosis. Intervention measures for infection control are crucial, namely sanitation improvement, control of domestic pig-breeding, detailed meat inspection, detection and treatment of tapeworm carriers, hand washing and health education.
癫痫是最常见的神经系统疾病之一，而由猪带绦虫感染中枢神经系统引起的神经囊尾蚴病目前是中南美洲、东亚、南亚和撒哈拉以南非洲继发性癫痫的主要原因。由于来自这些流行地区的移民增加，神经囊尾蚴病及随后的癫痫在发达国家也正成为日益严重的公共卫生问题。为了确定克罗地亚癫痫患者中猪带绦虫感染的患病率，进行了一项回顾性血清学研究。使用商业定性酶免疫测定法对总共770份血清样本进行了猪带绦虫IgG抗体检测。采用蛋白质印迹技术作为诊断的确证试验。临床确诊的癫痫患者中猪带绦虫感染的总体血清阳性率为1.5%。尽管结果表明这种绦虫感染在克罗地亚很少见，但本研究希望提高对预防措施重要性以及准确及时诊断益处的认识。感染控制的干预措施至关重要，即改善环境卫生、控制家庭养猪、详细的肉类检查、检测和治疗绦虫携带者、洗手和健康教育。
