Department of Medical Genetics, Ege University Faculty of Medicine, Izmir, Turkey.
J Neurooncol. 2012 Jan;106(1):53-8. doi: 10.1007/s11060-011-0644-z. Epub 2011 Jul 6.
Concerns about the health effects of radiofrequency (RF) waves have been raised because of the gradual increase in usage of cell phones, and there are scientific questions and debates about the safety of those instruments in daily life. The aim of this study is to evaluate the genotoxic effects of RF waves in an experimental brain cell culture model. Brain cell cultures of the mice were exposed to 10.715 GHz with specific absorbtion rate (SAR) 0.725 W/kG signals for 6 h in 3 days at 25°C to check for the changes in the micronucleus (MNi) assay and in the expression of 11 proapoptotic and antiapoptotic genes. It was found that MNi rate increased 11-fold and STAT3 expression decreased 7-fold in the cell cultures which were exposed to RF. Cell phones which spread RF may damage DNA and change gene expression in brain cells.
由于手机的使用逐渐增加，人们对射频 (RF) 波的健康影响产生了担忧，并且关于这些仪器在日常生活中的安全性存在科学问题和争论。本研究旨在评估 RF 波在实验性脑细胞培养模型中的遗传毒性作用。将小鼠脑细胞培养物暴露于特定吸收率 (SAR) 为 0.725 W/kg 的 10.715 GHz 射频信号下，每天 6 小时，共 3 天，在 25°C 下进行，以检查微核 (MNi) 测定和 11 个促凋亡和抗凋亡基因表达的变化。结果发现，暴露于 RF 的细胞培养物中的 MNi 率增加了 11 倍，STAT3 表达减少了 7 倍。传播 RF 的手机可能会损坏 DNA 并改变脑细胞中的基因表达。
