Institute of Chemistry of Biogenic Resources, Technische Universität München, Schulgasse 16, 94315 Straubing, Germany.
Appl Microbiol Biotechnol. 2011 Aug;91(4):937-47. doi: 10.1007/s00253-011-3438-5. Epub 2011 Jul 6.
Since its first description in the early 1960s, scleroglucan attracted much attention from both academia and industry. Scleroglucan is an exopolysaccharide secreted by the basidiomycete Sclerotium rolfsii and appreciated as a multipurpose compound applicable in many industrial fields, including oil industry, food industry and pharmacy. In this review, the current knowledge on scleroglucan chemistry, genetics, biosynthesis and production will be summarized and different application possibilities will be discussed. The biosynthesis of scleroglucan in S. rolfsii will be highlighted by recent transcriptomic data and linked to physiological data to better understand the biogenesis of scleroglucan and its link to the phytopathologic lifestyle of S. rolfsii.
自 20 世纪 60 年代初首次描述以来，纤维二糖吸引了学术界和工业界的广泛关注。纤维二糖是一种由担子菌胶红酵母分泌的胞外多糖，被认为是一种多用途化合物，可应用于许多工业领域，包括石油工业、食品工业和制药工业。在这篇综述中，将总结纤维二糖的化学、遗传学、生物合成和生产的最新知识，并讨论其不同的应用可能性。将通过最近的转录组数据突出显示胶红酵母中纤维二糖的生物合成，并将其与生理数据联系起来，以更好地理解纤维二糖的生物发生及其与胶红酵母植物病理生活方式的联系。
