[The effect of creatine phosphate on reflex transmission in the normal spinal cord and under hypoxic conditions].
作者信息
Limanskiĭ Iu P, Tamarova Z A, Piliavskiĭ A I, Oksamitnyĭ V N, Khasabov S G, Bulgakova N V
出版信息
Zh Vopr Neirokhir Im N N Burdenko. 1990 Jul-Aug(4):25-8.
PMID:2173305
Abstract
The effect of phosphocreatine on reflex transmission in the spinal cord was studied in rats in vivo and in vitro. Low concentrations (10(-8)-10(-6) M) of phosphocreatine facilitated while high concentrations (10(-4)-10(-3) M) inhibited the amplitude of mono- and polysynaptic reflexes. It was found that phosphocreatine decreases the inhibiting action of hypoxia on test responses and accelerates restoration of the reflex transmission in the spinal cord.
摘要
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