Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA.
Br J Nutr. 2012 Jan;107(1):146-54. doi: 10.1017/S0007114511002261. Epub 2011 Jun 27.
Fish proteins have been reported to be more satiating than meat proteins. The objective was to determine the effect of different animal protein pre-meals on satiety. A total of ten intact female hounds were fed pork loin, beef loin, chicken breast, salmon fillet or pollock fillet. Each pre-meal was fed to contain 100 g protein. Blood was collected at 0, 5, 15, 30, 60, 90 and 120 min postprandially and analysed for glucose, insulin, total ghrelin, active glucagon-like peptide-1 (GLP-1) and plasma amino acids (AA). Dogs were fed 2 × metabolisable energy, 3 h following the pre-meal, and intake was determined 30, 60, 180 and 1440 min after food presentation. Glucose decreased over time (P < 0·001), but was lowest (P = 0·01) when dogs consumed pollock or chicken. Insulin increased (P < 0·0001) over time, and was greater (P = 0·09) when dogs consumed salmon. GLP-1 increased (P < 0·001) over time, and was greatest (P = 0·04) when dogs consumed beef. Ghrelin decreased (P < 0·0001) over time for all pre-meals. The tryptophan:large neutral AA ratio tended to be greater (P = 0·08) when dogs consumed pork, salmon and pollock. Different protein sources may influence blood markers in dogs, but it does not appear that fish substrates have different satiating abilities than mammalian or avian sources.
鱼类蛋白比肉类蛋白更具饱腹感。本研究旨在确定不同动物蛋白预餐后对饱腹感的影响。将 10 只完整雌性猎犬分别喂食猪里脊、牛里脊、鸡胸肉、三文鱼和鳕鱼。每种预餐均含有 100g 蛋白质。在餐后 0、5、15、30、60、90 和 120min 采集血液，分析血糖、胰岛素、总胃饥饿素、活性胰高血糖素样肽-1（GLP-1）和血浆氨基酸（AA）。在预餐后 3h 给予猎犬 2×代谢能，在食物呈现后 30、60、180 和 1440min 测定摄入量。血糖随时间降低（P<0·001），但猎犬食用鳕鱼或鸡肉时最低（P=0·01）。胰岛素随时间增加（P<0·0001），猎犬食用三文鱼时更高（P=0·09）。GLP-1 随时间增加（P<0·001），猎犬食用牛肉时最高（P=0·04）。胃饥饿素随时间降低（P<0·0001），所有预餐均如此。色氨酸：大中性氨基酸比值在猎犬食用猪肉、三文鱼和鳕鱼时趋于更高（P=0·08）。不同的蛋白质来源可能会影响犬的血液标志物，但鱼类底物似乎没有比哺乳动物或禽类来源具有不同的饱腹感。
