Department of Biometry and Clinical Epidemiology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Angiology. 2012 May;63(4):315-9. doi: 10.1177/0003319711414868. Epub 2011 Jul 6.
Thromboangiitis obliterans (TAO) has traditionally been included among the diseases associated with Raynaud syndrome (RS). The prevalence of RS in patients with TAO is not well defined. The objective of this meta-analysis is to assess the prevalence of RS in patients with TAO. A literature search was performed for the studies dealing with RS and TAO. The studies provided sufficient data to estimate the prevalence of RS in patients with TAO. A total of 8 eligible studies, contributing data on 851 patients, were included in this meta-analysis. For TAO, a pooled prevalence of 28.1% and 95% confidence interval ([CI] = 0.158, 0.423) were obtained. Statistically publication bias was not present (P = .232). Despite some heterogeneity, there is a possible indication of an association between RS and patients with TAO.
血栓闭塞性脉管炎（TAO）传统上被认为是与雷诺综合征（RS）相关的疾病之一。RS 在 TAO 患者中的患病率尚未明确。本荟萃分析的目的是评估 TAO 患者中 RS 的患病率。对涉及 RS 和 TAO 的研究进行了文献检索。这些研究提供了足够的数据来估计 TAO 患者中 RS 的患病率。共有 8 项符合条件的研究，共纳入 851 例患者的数据，纳入本荟萃分析。TAO 的汇总患病率为 28.1%，95%置信区间（CI）为 0.158-0.423。统计学上不存在发表偏倚（P =.232）。尽管存在一定的异质性，但 RS 与 TAO 患者之间可能存在关联的迹象。
