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Knocking out the door to tunicamycin entry.

作者信息

Bassik Michael C, Kampmann Martin

机构信息

Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

出版信息

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11731-2. doi: 10.1073/pnas.1109035108. Epub 2011 Jul 6.

DOI:10.1073/pnas.1109035108
PMID:21734150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3141928/
Abstract
摘要

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本文引用的文献

1
A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin.一个单倍体遗传筛选确定了主要易化剂结构域包含 2A（MFSD2A）转运蛋白是应对衣霉素的关键介质。
Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11756-65. doi: 10.1073/pnas.1018098108. Epub 2011 Jun 15.
2
Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.通过深度测序对人类细胞中的全局基因进行敲除，以将基因分配到表型中。
Nat Biotechnol. 2011 May 29;29(6):542-6. doi: 10.1038/nbt.1857.
3
MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment.MFSD2A 是一个新的肺肿瘤抑制基因，调节细胞周期和基质附着。
Mol Cancer. 2010 Mar 17;9:62. doi: 10.1186/1476-4598-9-62.
4
Haploid genetic screens in human cells identify host factors used by pathogens.人类细胞中的单倍体遗传筛选可识别病原体所利用的宿主因子。
Science. 2009 Nov 27;326(5957):1231-5. doi: 10.1126/science.1178955.
5
A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2.一种针对具有融合性、源自内源性逆转录病毒的人内源性逆转录病毒包膜蛋白2的胎盘特异性受体。
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6
Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.Mfsd2a编码一种新型的含有主要易化子超家族结构域的蛋白质，在禁食和适应性产热过程中，该蛋白质在棕色脂肪组织中高度诱导表达。
Biochem J. 2008 Dec 15;416(3):347-55. doi: 10.1042/BJ20080165.
7
Ins and outs of major facilitator superfamily antiporters.主要易化子超家族反向转运蛋白的来龙去脉
Annu Rev Microbiol. 2008;62:289-305. doi: 10.1146/annurev.micro.61.080706.093329.
8
Signal integration in the endoplasmic reticulum unfolded protein response.内质网未折叠蛋白反应中的信号整合
Nat Rev Mol Cell Biol. 2007 Jul;8(7):519-29. doi: 10.1038/nrm2199.
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The unfolded protein response: a stress signaling pathway critical for health and disease.未折叠蛋白反应：一条对健康和疾病至关重要的应激信号通路。
Neurology. 2006 Jan 24;66(2 Suppl 1):S102-9. doi: 10.1212/01.wnl.0000192306.98198.ec.
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The role of the unfolded protein response in tumour development: friend or foe?未折叠蛋白反应在肿瘤发展中的作用：朋友还是敌人？
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