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Superoxide anion radical induces lipid phase transitions that mimic temperature-induced phase-transition phenomenon of membrane lipids.

作者信息

Kumar G P, Tillo N, Laloraya M, Nivsarkar M, Verma S, Singh A

机构信息

School of Life Sciences, Devi Ahilya Vishwavidyalaya, Indore, India.

出版信息

Biochem Biophys Res Commun. 1990 Oct 30;172(2):601-6. doi: 10.1016/0006-291x(90)90716-z.

DOI:10.1016/0006-291x(90)90716-z
PMID:2173573
Abstract

A biological membrane is shown to undergo lipid-phase transition leading to increased membrane fluidity when exposed to extraneously generated superoxide anion radical. This phase-transition is several folds higher in magnitude when compared to the temperature-induced fluidity change at the transition temperatures. This finding could have significant importance since an altered membrane configuration may involve aspects of biochemistry, biophysics or physiology.

摘要

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