Ichikawa Yoshikazu, Takanashi Taiji, Mihara Etsuko, Shoji Takuro, Kinoshita Kaori, Shimizu Yasutaka
Department of Ophthalmology, Matsue Red Cross Hospital.
Nippon Ganka Gakkai Zasshi. 2011 Jun;115(6):535-40.
Alexia with agraphia usually represents damage in angular gyrus. We report an unusual case of alexia with agraphia caused by a posterior inferior temporal lesion.
A 82-year-old, right-handed man was admitted because of reading disorder. Visual acuity was 0.7 OD and 0.7 OS. Goldmann perimetry revealed right homonymous upper quadrantanopsia. Standard Language Test of Aphasia revealed mild anomia and severe alexia with agraphia for kanji. Magnetic resonance imaging demonstrated left temporal and posterior infarction in the posterior cerebral artery region. Single photon emission computed tomography revealed decreased blood flow in the left inferior temporal, parahippocampal, fusiform, lingual and inferior occipital gyri. There were no significant lesions nor any decreased of blood flow in the angular gyrus.
It is suggested that reading and writing of ideograms such as Kanji is related not only to the angular gyrus but also to the posterior inferior temporal lobe and medial posterior lobe of the visual cortex.
失读伴失写通常提示角回受损。我们报告一例由颞叶后下部病变引起的失读伴失写的罕见病例。
一名82岁右利手男性因阅读障碍入院。视力右眼0.7,左眼0.7。Goldmann视野检查显示右侧同向性上象限盲。标准失语症语言测试显示轻度命名性失语和严重的汉字失读伴失写。磁共振成像显示大脑后动脉区域左侧颞叶及后部梗死。单光子发射计算机断层扫描显示左侧颞下回、海马旁回、梭状回、舌回及枕下回血流减少。角回无明显病变及血流减少。
提示汉字等表意文字的阅读和书写不仅与角回有关,还与颞叶后下部及视觉皮层内侧后部有关。