Sakurai Y, Sakai K, Sakuta M, Iwata M
Department of Neurology, University of Tokyo, School of Medicine, Japan.
J Neurol Neurosurg Psychiatry. 1994 May;57(5):609-13. doi: 10.1136/jnnp.57.5.609.
The case is described of a patient with alexia and agraphia for kanji, and severe anomia after a subcortical haemorrhage in the left posterior inferior temporal area. Magnetic resonance imaging at four months after onset showed a lesion in the inferior temporal and fusiform gyri, extending from the temporo-occipital junction toward the anterior third of the temporal lobe. Comparison with other reported cases of alexia with agraphia and anomia made it clear that when accompanied by severe anomia, the lesions extended either forward to the anterior part of the middle temporal gyrus or medially to the parahippocampal gyrus. It is suggested that the disconnection of association fibres between the parahippocampal, fusiform, middle, and inferior temporal gyri, especially between the parahippocampal gyrus and the other temporal gyri, or the cortical damage to the posterior part of these gyri is essential for the production of anomia.
本文描述了一名患者，其患有汉字失读症和失写症，并在左颞下后区发生皮质下出血后出现严重命名性失语。发病四个月后的磁共振成像显示颞下回和梭状回有病变，从颞枕交界区延伸至颞叶前三分之一处。与其他已报道的失读伴失写和命名性失语病例相比，明确显示当伴有严重命名性失语时，病变要么向前延伸至颞中回前部，要么向内延伸至海马旁回。提示海马旁回、梭状回、颞中回和颞下回之间，尤其是海马旁回与其他颞回之间的联合纤维中断，或这些脑回后部的皮质损伤是命名性失语产生的关键。
