Developmental and Life-course Research Group, Department of Psychiatry, University of Cambridge, Cambridge, UK.
BMC Psychiatry. 2011 Jul 7;11:109. doi: 10.1186/1471-244X-11-109.
Adverse family experiences in early life are associated with subsequent psychopathology. This study adds to the growing body of work exploring the nature and associations between adverse experiences over the childhood years.
Primary carers of 1143 randomly recruited 14-year olds in Cambridgeshire and Suffolk, UK were interviewed using the Cambridge Early Experiences Interview (CAMEEI) to assess family-focused adversities. Adversities were recorded retrospectively in three time periods (early and later childhood and early adolescence). Latent Class Analysis (LCA) grouped individuals into adversity classes for each time period and longitudinally. Adolescents were interviewed to generate lifetime DSM-IV diagnoses using the K-SADS-PL. The associations between adversity class and diagnoses were explored.
LCA generated a 4-class model for each time period and longitudinally. In early childhood 69% were allocated to a low adversity class; a moderate adversity class (19%) showed elevated rates of family loss, mild or moderate family discord, financial difficulties, maternal psychiatric illness and higher risk for paternal atypical parenting; a severe class (6%) experienced higher rates on all indicators and almost exclusively accounted for incidents of child abuse; a fourth class, characterised by atypical parenting from both parents, accounted for the remaining 7%. Class membership was fairly stable (~ 55%) over time with escape from any adversity by 14 years being uncommon. Compared to those in the low class, the odds ratio for reported psychopathology in adolescents in the severe class ranged from 8 for disruptive behaviour disorders through to 4.8 for depressions and 2.0 for anxiety disorders. Only in the low adversity class did significantly more females than males report psychopathology.
Family adversities in the early years occur as multiple rather than single experiences. Although some children escape adversity, for many this negative family environment persists over the first 15 years of life. Different profiles of family risk may be associated with specific mental disorders in young people. Sex differences in psychopathologies may be most pronounced in those exposed to low levels of family adversities.
早年生活中的不良家庭经历与随后的精神病理学有关。本研究增加了越来越多的工作,探索了童年时期不良经历的性质和关联。
在英国剑桥郡和萨福克郡,随机招募了 1143 名 14 岁的儿童,他们的主要照顾者接受了剑桥早期经验访谈(CAMEEI),以评估以家庭为中心的逆境。逆境在三个时间段(早期、后期儿童期和青春期早期)中进行回顾性记录。潜在类别分析(LCA)将个体按每个时间段和纵向的逆境类别分组。青少年接受访谈,使用 K-SADS-PL 生成终生 DSM-IV 诊断。探讨了逆境类别与诊断之间的关系。
LCA 为每个时间段和纵向生成了一个 4 类模型。在儿童早期,69%的人被分配到低逆境类别;中度逆境类别(19%)显示出家庭丧失、轻度或中度家庭不和、经济困难、母亲精神疾病和父亲非典型育儿的更高风险;严重类别(6%)经历了所有指标的更高比率,几乎完全归因于儿童虐待事件;第四类,由父母双方的非典型育儿组成,占其余的 7%。随着时间的推移,类别的成员相对稳定(~55%),14 岁时逃避任何逆境并不常见。与低类别相比,在严重类别中报告精神病理学的青少年的优势比范围从破坏性行为障碍的 8 到抑郁症的 4.8 和焦虑障碍的 2.0。只有在低逆境类别中,报告精神病理学的女性比例显著高于男性。
早年的家庭逆境是多种而不是单一的经历。尽管一些儿童逃脱了逆境,但对许多人来说,这种负面家庭环境在生命的头 15 年中持续存在。不同的家庭风险特征可能与年轻人的特定精神障碍有关。在暴露于低水平家庭逆境的人群中,性别差异在精神病理学中可能最为明显。