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韩国新引入的破伤风、白喉、无细胞百日咳联合疫苗(Tdap疫苗)使用建议。

Recommendation for the use of newly introduced Tdap vaccine in Korea.

作者信息

Choi Kyong Min, Kim Kyung Hyo, Kim Yae-Jean, Kim Jong-Hyun, Park Su Eun, Lee Hoan Jong, Eun Byung Wook, Jo Dae Sun, Choi Eun Hwa, Hong Young Jin

机构信息

The Committee on Infectious Diseases, the Korean Pediatric Society, Korea.

出版信息

Korean J Pediatr. 2011 Apr;54(4):141-5. doi: 10.3345/kjp.2011.54.4.141. Epub 2011 Apr 30.

Abstract

Pertussis is an acute respiratory infection characterized by paroxysmal cough and inspiratory whoop for over 2 weeks. The incidence of pertussis has decreased markedly after the introduction of DTwP/DTaP vaccine, but the incidence of pertussis has increased steadily among young infant and among adolescents and adults in many countries. Td vaccine was used in this age group but the increase in pertussis has lead to the development of a Tdap vaccine. The Tdap vaccine is a Td vaccine with a pertussis vaccine added and is thought to decrease the incidence and transmission of pertussis in the respective age group. In Korea, two products are approved by the KOREA FOOD & DRUG ADMINISTRATION, which are ADACEL™ (Sanofi-Pasteur, Totonto, Ontario, Canada) and BOOSTRIX® (GlaxoSmithKline Biologicals, Rixensart, Belgium) for those aged between 11-64. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.

摘要

百日咳是一种急性呼吸道感染,其特征为阵发性咳嗽和吸气性吼声,持续超过2周。在引入白百破/无细胞百白破疫苗后,百日咳的发病率显著下降,但在许多国家,婴儿以及青少年和成人中的百日咳发病率却在稳步上升。该年龄组此前使用的是破伤风类毒素疫苗(Td),但百日咳发病率的上升促使了吸附无细胞百白破联合疫苗(Tdap)的研发。Tdap疫苗是一种添加了百日咳疫苗的Td疫苗,被认为可降低相应年龄组中百日咳的发病率和传播率。在韩国,韩国食品药品管理局批准了两种产品,即适用于11至64岁人群的ADACEL™(赛诺菲巴斯德公司,加拿大安大略省多伦多市)和BOOSTRIX®(葛兰素史克生物制品公司,比利时里克森萨特)。本报告总结了韩国儿科学会传染病委员会批准的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dddd/3127146/f9cfd52aaf22/kjped-54-141-g001.jpg

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