HIV 病的耳鼻喉科表现——临床方面和治疗。
Otolaryngologic manifestations in HIV disease--clinical aspects and treatment.
机构信息
Otorhinolaryngology Department, University of São Paulo.
出版信息
Braz J Otorhinolaryngol. 2011 Jun;77(3):391-400. doi: 10.1590/s1808-86942011000300020.
Abstract
UNLABELLED
HIV is a pandemic infection with cases notified in almost all countries. The reported prevalence of symptoms in the head and neck is about 80%; otolaryngologists may be the first physician to see such patients. Oral manifestations are the most common, followed by neck and sinus manifestations. Otolaryngologic symptoms may be important signs of antiretroviral therapy failure. Symptoms are present in acute infections and advanced cases.
OBJECTIVE
To describe new approaches in the past five years for the treatment of the most frequent otolaryngologic manifestations in HIV patients.
METHODS
Systematic reviews and case series published in English and Portuguese from January 2002 to October 2007 including the most common otolaryngology manifestations were selected.
CONCLUSION
Otolaryngologic manifestations are common and ENT specialists must be prepared to identify such cases.
摘要
未加说明
HIV 是一种在几乎所有国家都有病例报告的流行感染。据报道，头部和颈部的症状发生率约为 80%；耳鼻喉科医生可能是最先看到此类患者的医生。口腔表现最为常见，其次是颈部和鼻窦表现。耳鼻喉科症状可能是抗逆转录病毒治疗失败的重要标志。这些症状存在于急性感染和晚期病例中。
目的
描述过去五年中治疗 HIV 患者最常见耳鼻喉科表现的新方法。
方法
选择 2002 年 1 月至 2007 年 10 月间发表的英文和葡萄牙文的系统评价和病例系列，包括最常见的耳鼻喉科表现。
结论
耳鼻喉科表现较为常见，耳鼻喉科医生必须做好识别此类病例的准备。
相似文献
1
Otolaryngologic manifestations in HIV disease--clinical aspects and treatment.HIV 病的耳鼻喉科表现——临床方面和治疗。
Braz J Otorhinolaryngol. 2011 Jun;77(3):391-400. doi: 10.1590/s1808-86942011000300020.
2
[Overview of head and neck clinical features related to HIV/AIDS].[与人类免疫缺陷病毒/获得性免疫缺陷综合征相关的头颈部临床特征概述]
Rev Med Suisse. 2024 Oct 2;20(889):1756-1760. doi: 10.53738/REVMED.2024.20.889.1756.
3
Imaging of otolaryngologic manifestations of HIV infection.人类免疫缺陷病毒感染的耳鼻咽喉科表现的影像学检查
Neuroimaging Clin N Am. 1997 May;7(2):375-99.
4
HIV manifestations in otolaryngology.耳鼻咽喉科中的HIV表现
Am J Otolaryngol. 2006 May-Jun;27(3):179-85. doi: 10.1016/j.amjoto.2005.09.011.
5
Pediatric Human Immunodeficiency Virus and Otolaryngologic Manifestations: An Analysis of Hospital Admissions From 1997 to 2012.儿科人类免疫缺陷病毒与耳鼻喉表现：1997 年至 2012 年住院患者分析。
Laryngoscope. 2019 Nov;129(11):E377-E382. doi: 10.1002/lary.27778. Epub 2019 Jan 22.
6
Otolaryngological, head and neck manifestations in HIV-infected patients seen at Steve Biko Academic Hospital in Pretoria, South Africa.南非比勒陀利亚史蒂夫·比科学术医院就诊的 HIV 感染患者的耳鼻喉和头颈部表现。
S Afr Med J. 2013 May 16;103(7):464-6. doi: 10.7196/samj.6786.
7
Age of Bioterrorism: Are You Prepared? Review of Bioweapons and Their Clinical Presentation for Otolaryngologists.生物恐怖主义时代：你准备好了吗？耳鼻咽喉科医生对生物武器及其临床表现的综述。
Otolaryngol Head Neck Surg. 2014 Aug;151(2):208-14. doi: 10.1177/0194599814531907. Epub 2014 Apr 22.
8
Head and neck manifestations of HIV infection: a preliminary study.HIV感染的头颈部表现：一项初步研究。
J Indian Med Assoc. 2003 Feb;101(2):93-5.
9
[A practically orientated clinical HIV update for ENT physicians].[面向耳鼻喉科医生的实用临床艾滋病最新资讯]
HNO. 2015 Jan;63(1):63-72; quiz 73. doi: 10.1007/s00106-014-2937-y.
10
Otolaryngologic manifestations of human immunodeficiency virus infection.人类免疫缺陷病毒感染的耳鼻喉科表现。
Med Clin North Am. 1999 Jan;83(1):303-15, xii. doi: 10.1016/s0025-7125(05)70103-6.
引用本文的文献
1
Otolaryngological Manifestations and Associated Biochemical, Hematological, and Immunological Profiles in HIV-Positive Patients in Vietnam.越南HIV阳性患者的耳鼻喉科表现及相关生化、血液学和免疫学特征
Med Arch. 2025;79(3):220-226. doi: 10.5455/medarh.2025.79.220-226.
2
A Cross-Sectional Study of Audiological Assessment in HIV Positive Children.一项关于HIV阳性儿童听力评估的横断面研究。
Indian J Otolaryngol Head Neck Surg. 2025 Mar;77(3):1360-1366. doi: 10.1007/s12070-025-05342-6. Epub 2025 Jan 18.
3
Hospitalizations for Acute Otitis and Sinusitis in Patients Living with HIV: A Retrospective Analysis of a Tertiary Center in Romania.罗马尼亚一家三级中心对感染艾滋病毒患者的急性中耳炎和鼻窦炎住院情况进行的回顾性分析。
J Clin Med. 2024 Jun 6;13(11):3346. doi: 10.3390/jcm13113346.
4
CMV sinusitis, an overlooked diagnosis, a predisposing condition or is it a bystander? A Case report and review of the literature.巨细胞病毒鼻窦炎，是一种被忽视的诊断、一种易感因素还是仅仅是个旁观者？一例病例报告及文献综述。
IDCases. 2022 Nov 1;30:e01633. doi: 10.1016/j.idcr.2022.e01633. eCollection 2022.
5
Mucosal immune cell populations and the bacteriome of adenoids and tonsils from people living with HIV on suppressive antiretroviral therapy.接受抑制性抗逆转录病毒治疗的HIV感染者腺样体和扁桃体的黏膜免疫细胞群体及细菌群落
Front Microbiol. 2022 Aug 11;13:958739. doi: 10.3389/fmicb.2022.958739. eCollection 2022.
6
Prevalence of Ear Nose and Throat (ENT) Manifestations Among HIV Seropositive Patients at a Tertiary Hospital in Northern Tanzania: A Descriptive Cross-Sectional Study.坦桑尼亚北部一家三级医院中HIV血清阳性患者的耳鼻喉（ENT）表现患病率：一项描述性横断面研究。
HIV AIDS (Auckl). 2020 Sep 16;12:425-429. doi: 10.2147/HIV.S260908. eCollection 2020.
7
Audiological assessment of children with HIV/AIDS: a meta-analysis.HIV/AIDS 患儿的听力学评估：一项荟萃分析。
J Pediatr (Rio J). 2020 Sep-Oct;96(5):537-545. doi: 10.1016/j.jped.2019.11.003. Epub 2020 Jan 3.
8
[Immunodeficiency in chronic rhinosinusitis : An important and often underestimated cause].[慢性鼻-鼻窦炎中的免疫缺陷：一个重要且常被低估的病因]
HNO. 2019 Sep;67(9):715-730. doi: 10.1007/s00106-019-0719-2.
9
Otorhinolaryngological profile and surgical intervention in patients with HIV/AIDS.HIV/AIDS 患者的耳鼻喉科特征及外科干预。
Sci Rep. 2018 Aug 13;8(1):12045. doi: 10.1038/s41598-018-27761-y.
10
Emerging and re-emerging infectious disease in otorhinolaryngology.耳鼻咽喉科新发和再发传染病
Acta Otorhinolaryngol Ital. 2018 Apr;38(SUPPL. 1):S1-S106. doi: 10.14639/0392-100X-suppl.1-38-2018.
本文引用的文献
1
2
Oral lesions as clinical markers of highly active antiretroviral therapy failure: a nested case-control study in Mexico City.口腔病变作为高效抗逆转录病毒治疗失败的临床标志物：墨西哥城的一项巢式病例对照研究。
Clin Infect Dis. 2007 Oct 1;45(7):925-32. doi: 10.1086/521251. Epub 2007 Aug 23.
3
Allergen immunotherapy in a patient with human immunodeficiency virus: effect on T-cell activation and viral replication.人类免疫缺陷病毒患者的变应原免疫疗法：对T细胞活化和病毒复制的影响。
Ann Allergy Asthma Immunol. 2007 May;98(5):495-7. doi: 10.1016/S1081-1206(10)60767-3.
4
Management of oral lesions in HIV-positive patients.HIV阳性患者口腔病变的管理。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103 Suppl:S50.e1-23. doi: 10.1016/j.tripleo.2006.11.002.
5
Otitis media in Brazilian human immunodeficiency virus infected children undergoing antiretroviral therapy.接受抗逆转录病毒治疗的巴西感染人类免疫缺陷病毒儿童的中耳炎
J Laryngol Otol. 2007 Nov;121(11):1048-54. doi: 10.1017/S0022215107006093. Epub 2007 Feb 26.
6
Bilateral peripheral facial palsy in a patient with Human Immunodeficiency Virus (HIV) infection.一名感染人类免疫缺陷病毒（HIV）的患者出现双侧周围性面瘫。
Yonsei Med J. 2006 Oct 31;47(5):745-7. doi: 10.3349/ymj.2006.47.5.745.
7
Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children.成人及儿童HIV感染相关口咽念珠菌病的预防与管理干预措施。
Cochrane Database Syst Rev. 2006 Jul 19(3):CD003940. doi: 10.1002/14651858.CD003940.pub2.
8
Oral candidosis and oral hairy leukoplakia as predictors of HAART failure in Brazilian HIV-infected patients.口腔念珠菌病和口腔毛状白斑作为巴西HIV感染患者高效抗逆转录病毒治疗失败的预测指标。
Oral Dis. 2006 Jul;12(4):402-7. doi: 10.1111/j.1601-0825.2005.01214.x.
9
Changing spectrum of the diffuse infiltrative lymphocytosis syndrome.弥漫性浸润性淋巴细胞增多综合征的变化谱
Arthritis Rheum. 2006 Jun 15;55(3):466-72. doi: 10.1002/art.21980.
10
Oral EBV and KSHV infection in HIV.人类免疫缺陷病毒（HIV）感染中的口腔EB病毒和卡波西肉瘤相关疱疹病毒感染
Adv Dent Res. 2006 Apr 1;19(1):91-5. doi: 10.1177/154407370601900118.
Zotero 插件