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温针艾灸对改善结直肠癌术后患者胃肠及免疫功能的影响

[Effects of warming needle moxibustion on improvement of gastrointestinal and immune function in patients with postoperation of colorectal cancer].

作者信息

Zhang Shuang-yan, Du Ye-qin

机构信息

Department of Integrated Chinese and Western Medicine, The Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi 830011, China.

出版信息

Zhongguo Zhen Jiu. 2011 Jun;31(6):513-7.

Abstract

OBJECTIVE

To verify the clinical therapeutic effect of warming needle moxibustion on improvement of the gastrointestinal and immune function in patients with postoperation of colorectal cancer.

METHODS

One hundred and five patients with postoperation of colorectal cancer were randomly divided into an acupuncture and moxibustion group, a Chinese medicine group and a routine treatment group, 35 cases in each group. They were all treated with gastrointestinal decompression and fluid replacement after operation. The acupuncture and moxibustion group was also treated with warming needle moxibustion on the 1st day after operation, and Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) etc. were selected, once a day for 10 days, and the Chinese medicine group with Simo Decoction oral solution, three times daily for 10 days. The gastrointestinal function, peripheral blood components and changes of T lymphocyte and NK cells in postoperative patients were observed.

RESULTS

The time of the first bowel sound, exhaust and defecation in the acupuncture and moxibustion group were all shorter than those in the Chinese medicine group and the routine treatment group (P<0.05, P<0.01). On the 10th day after operation, the percentages distribution of lymphocyte and neutrophil in the acupuncture and moxibustion group were better than those in the Chinese medicine group and the routine treatment group (all P<0.05). The acupuncture and moxibustion group was also superior to the Chinese medicine group and the routine treatment group in improving the subgroup of T lymphocyte, NK cells and the digestive system symptoms (all P<0.05).

CONCLUSION

Warming needle moxibustion has a good therapeutic effect on gastrointestinal function and can regulate bidirectionally peripheral blood lymphocyte and neutrophile granulocyte and improve the T lymphocyte subgroup and NK cells so as to promote the recovery of immune function in patients with colorectal cancer after operation.

摘要

目的

验证温针艾灸对改善结直肠癌术后患者胃肠功能及免疫功能的临床治疗效果。

方法

将105例结直肠癌术后患者随机分为针灸组、中药组和常规治疗组,每组35例。术后均给予胃肠减压及补液治疗。针灸组于术后第1天加用温针艾灸,选取足三里(ST36)、上巨虚(ST37)、下巨虚(ST39)等穴位,每日1次,共10天;中药组给予四磨汤口服液口服,每日3次,共10天。观察术后患者的胃肠功能、外周血成分及T淋巴细胞和NK细胞的变化。

结果

针灸组首次肠鸣音、排气及排便时间均短于中药组和常规治疗组(P<0.05,P<0.01)。术后第10天,针灸组淋巴细胞和中性粒细胞百分比分布优于中药组和常规治疗组(均P<0.05)。针灸组在改善T淋巴细胞亚群、NK细胞及消化系统症状方面也优于中药组和常规治疗组(均P<0.05)。

结论

温针艾灸对胃肠功能有良好的治疗作用,可双向调节外周血淋巴细胞和中性粒细胞,改善T淋巴细胞亚群及NK细胞,促进结直肠癌术后患者免疫功能的恢复。

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