Department of Orthopedic Surgery, Keio University, Japan.
J Neurosurg Spine. 2011 Oct;15(4):380-5. doi: 10.3171/2011.6.SPINE10816. Epub 2011 Jul 8.
The aim of this study was to evaluate the outcomes of fusion surgery in patients with ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL) and to identify factors significantly related to surgical outcomes.
The study included 76 patients (34 men and 42 women with a mean age of 56.3 years) who underwent fusion surgery for T-OPLL at 7 spine centers during the 5-year period from 2003 to 2007. The authors evaluated the patient demographic data, underlying disease, preoperative comorbidities, history of spinal surgery, radiological findings, surgical methods, surgical outcomes, and complications. Surgical outcomes were assessed using the Japanese Orthopaedic Association (JOA) scale score for thoracic myelopathy (11 points) and the recovery rate.
The mean JOA scale score was 4.6 ± 2.1 points preoperatively and 7.7 ± 2.5 points at the time of the final follow-up examination, yielding a mean recovery rate of 45.4% ± 39.1%. The recovery rates by surgical method were 38.5% ± 37.8% for posterior decompression and fusion, 65.0% ± 35.6% for anterior decompression and fusion via an anterior approach, 28.8% ± 41.2% for anterior decompression via a posterior approach, and 57.5% ± 41.1% for circumferential decompression and fusion. The recovery rate was significantly higher in patients without diabetes mellitus (DM) than in those with DM. One or more complications were experienced by 31 patients (40.8%), including 20 patients with postoperative neurological deterioration, 7 with dural tears, 5 with epidural hematomas, 4 with respiratory complications, and 10 with other complications.
The outcomes of fusion surgery for T-OPLL were favorable. The absence of DM correlated with better outcomes. However, a high rate of complications was associated with the fusion surgery.
本研究旨在评估胸椎后纵韧带骨化(T-OPLL)患者融合手术的结果,并确定与手术结果显著相关的因素。
本研究纳入了 76 名患者(34 名男性和 42 名女性,平均年龄为 56.3 岁),他们在 2003 年至 2007 年的 5 年间在 7 个脊柱中心接受了 T-OPLL 的融合手术。作者评估了患者的人口统计学数据、基础疾病、术前合并症、脊柱手术史、影像学发现、手术方法、手术结果和并发症。使用日本矫形协会(JOA)胸髓病量表评分(11 分)和恢复率评估手术结果。
术前平均 JOA 量表评分为 4.6±2.1 分,最终随访时评分为 7.7±2.5 分,平均恢复率为 45.4%±39.1%。根据手术方法,后路减压融合的恢复率为 38.5%±37.8%,前路减压融合的恢复率为 65.0%±35.6%,后路前路减压的恢复率为 28.8%±41.2%,环减压融合的恢复率为 57.5%±41.1%。无糖尿病(DM)患者的恢复率明显高于 DM 患者。31 名患者(40.8%)出现 1 种或多种并发症,包括 20 名术后神经功能恶化患者、7 名硬脊膜撕裂患者、5 名硬膜外血肿患者、4 名呼吸并发症患者和 10 名其他并发症患者。
T-OPLL 融合手术的结果是有利的。无 DM 与更好的结果相关。然而,融合手术与较高的并发症发生率相关。