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精神分裂症或双相情感障碍患者的预期寿命。

Life expectancy among persons with schizophrenia or bipolar affective disorder.

机构信息

National Centre for Register-Based Research, Aarhus University, Taasingegade 1, 8000 Aarhus C, Denmark.

出版信息

Schizophr Res. 2011 Sep;131(1-3):101-4. doi: 10.1016/j.schres.2011.06.008. Epub 2011 Jul 7.

Abstract

CONTEXT

Mortality rates among individuals with schizophrenia or bipolar disorder are elevated compared to the general population.

OBJECTIVE

The objective was to estimate life-expectancy (average age at death) among these persons and make a comparison to people in the general population.

METHODS

Life-expectancy was calculated by means of survival analysis techniques using the entire Danish population as a cohort.

RESULTS

Life-expectancy was 18.7 years shorter for schizophrenic men compared to men in the general population. Corresponding numbers for schizophrenic women was 16.3 years, for bipolar men 13.6 years, and for bipolar women 12.1 years.

CONCLUSIONS

Life-expectancy was much shorter in persons with schizophrenia or bipolar disorder. Excess mortality from physical diseases and medical conditions exerts a far greater influence on the curtailed life-expectancy, when compared against the impact of death by external causes.

摘要

背景

与普通人群相比,精神分裂症或双相情感障碍患者的死亡率较高。

目的

旨在估算这些人群的预期寿命(平均死亡年龄),并与普通人群进行比较。

方法

使用生存分析技术,以整个丹麦人群作为队列来计算预期寿命。

结果

与普通人群相比,男性精神分裂症患者的预期寿命缩短了 18.7 年。相应的女性精神分裂症患者为 16.3 年,男性双相情感障碍患者为 13.6 年,女性双相情感障碍患者为 12.1 年。

结论

精神分裂症或双相情感障碍患者的预期寿命明显缩短。与外部原因导致的死亡相比,身体疾病和医疗状况导致的过度死亡对预期寿命的缩短影响更大。

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