Department of Anesthesiology, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USA.
J Clin Anesth. 2011 Aug;23(5):398-402. doi: 10.1016/j.jclinane.2010.07.007. Epub 2011 Jul 8.
Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.
在肝移植期间，仅有不到 80 例描述了心内血栓形成和术中肺血栓栓塞症。我们介绍了一位患者，他在术中发生了暴发性心内和主动脉血栓形成，并且在术前采集的血浆中发现了高抗心磷脂免疫球蛋白 M 浓度和高纤维蛋白溶解标志物。讨论了存在循环抗磷脂抗体时的止血治疗和灾难性抗磷脂综合征的发病机制。
