Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Curr Opin Biotechnol. 2011 Oct;22(5):618-26. doi: 10.1016/j.copbio.2011.06.010.
Enzymes from hyperthermophiles display extreme (thermo)stability and a wide range of enzymes have been examined to explore their potential for various biotechnological processes. In addition, recent years have witnessed the development of genetic systems in a number of hyperthermophilic archaea. This has provided the means to initiate cell engineering studies in these organisms. Biofuel production is now an important topic in microbial biotechnology, and the hydrogen producing capabilities of (hyper)thermophiles, as well as their thermostable hydrogenases, are now attracting much attention.
嗜热菌来源的酶具有极端的（热）稳定性，人们已经对多种酶进行了研究，以探索它们在各种生物技术过程中的应用潜力。此外，近年来，许多嗜热古菌中已经开发出了遗传系统。这为在这些生物体中开展细胞工程研究提供了手段。生物燃料生产现在是微生物生物技术的一个重要课题，（嗜）热菌的产氢能力及其热稳定性氢化酶现在引起了广泛关注。
