Kapil S, Trent A M, Goyal S M
Department of Veterinary Diagnostic Investigation, College of Veterinary Medicine, University of Minnesota, St. Paul.
Arch Virol. 1990;115(1-2):127-32. doi: 10.1007/BF01310629.
Following oral inoculation, the excretion of a virulent or an attenuated strain of bovine coronavirus in calf feces and their persistence in spiral colon, ileum, and jejunum were studied using hemagglutination and direct fluorescent antibody tests, respectively. The virus was excreted in feces for only 3 days at high titers and then intermittently at low titers. However, viral antigen was detected in crypt or Peyer's patches for at least 3 weeks after infection in 1 of 3 calves given virulent virus and 1 of 2 calves given attenuated virus.
经口服接种后，分别采用血凝试验和直接荧光抗体试验，研究了牛冠状病毒强毒株或弱毒株在犊牛粪便中的排泄情况及其在螺旋结肠、回肠和空肠中的持续存在情况。病毒在粪便中高滴度排泄仅持续3天，之后以低滴度间歇性排泄。然而，在接种强毒病毒的3头犊牛中的1头以及接种弱毒病毒的2头犊牛中的1头，感染后至少3周内在隐窝或派伊尔氏淋巴集结中检测到病毒抗原。
