Infectious Diseases Research Center, Babol Medical University, Babol, 4717641367, Iran.
Trans R Soc Trop Med Hyg. 2011 Sep;105(9):540-2. doi: 10.1016/j.trstmh.2011.06.003. Epub 2011 Jul 13.
From April 2000 to March 2010, 19 pregnant women with brucellosis were evaluated, treated and followed up. Ten (53%) pregnant women had spontaneous abortions. Six of eleven (55%) women infected in the first trimester had a spontaneous abortion. After treatment, all subsequently became pregnant and gave birth to normal babies. Among 13 patients who received cotrimoxazole plus rifampin, only four (31%) aborted and nine mothers had normal term deliveries. Two patients with recurrent abortions had brucellosis and became pregnant and gave birth after treatment. The brucellosis screening program for pregnant women and those with spontaneous abortion is necessary in brucellosis endemic regions.
从 2000 年 4 月至 2010 年 3 月,对 19 例布鲁氏菌病孕妇进行了评估、治疗和随访。10 例(53%)孕妇发生自然流产。11 例(55%)于妊娠早期感染的孕妇中有 6 例发生自然流产。治疗后,所有孕妇均再次妊娠并分娩正常婴儿。在接受复方磺胺甲噁唑加利福平治疗的 13 例患者中,仅 4 例(31%)发生流产,9 例产妇足月分娩。2 例反复流产的患者在治疗后再次妊娠并分娩。布鲁氏菌病流行地区有必要对孕妇和自然流产患者进行布鲁氏菌病筛查。