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新型抗植物病原化合物 2-庚基-5-己基呋喃-3-羧酸,由新分离的假单胞菌 SJT25 菌株产生。

Novel antiphytopathogenic compound 2-heptyl-5-hexylfuran-3-carboxylic acid, produced by newly isolated Pseudomonas sp. strain SJT25.

机构信息

State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

出版信息

Appl Environ Microbiol. 2011 Sep;77(17):6253-7. doi: 10.1128/AEM.00443-11. Epub 2011 Jul 8.

Abstract

Pseudomonas sp. strain SJT25, which strongly antagonizes plant pathogens, was isolated from rice rhizosphere soil by a bioactivity-guided approach. A novel antiphytopathogenic compound was isolated from the fermentation broth of Pseudomonas sp. SJT25 and identified as 2-heptyl-5-hexylfuran-3-carboxylic acid. This compound showed antimicrobial activities both in vitro and in vivo.

摘要

由生物活性导向的方法从水稻根际土壤中分离出一株强烈拮抗植物病原菌的假单胞菌(Pseudomonas sp.)菌株 SJT25。从假单胞菌 SJT25 的发酵液中分离得到一种新型抗植物病原菌化合物,鉴定为 2-庚基-5-己基呋喃-3-羧酸。该化合物在体外和体内均表现出抗菌活性。

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