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Identification of an antifungal metabolite produced by a potential biocontrol Actinomyces strain A01.鉴定一株潜在生防放线菌 A01 产生的抗真菌代谢产物。
Braz J Microbiol. 2008 Oct;39(4):701-7. doi: 10.1590/S1517-838220080004000020. Epub 2008 Dec 1.
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Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria.合成 N-取代的 2-[(1E)-烯基]-4-(1H)-喹啉衍生物作为抗非结核分枝杆菌的抗分枝杆菌药物。
Eur J Med Chem. 2011 Jun;46(6):2091-101. doi: 10.1016/j.ejmech.2011.02.062. Epub 2011 Mar 3.
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Myxobacterial secondary metabolites: bioactivities and modes-of-action.粘细菌次级代谢产物：生物活性与作用方式
Nat Prod Rep. 2010 Sep;27(9):1276-95. doi: 10.1039/c001260m. Epub 2010 Jun 3.
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Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics.芽孢杆菌和假单胞菌脂肽的天然功能：不止是表面活性剂和抗生素。
FEMS Microbiol Rev. 2010 Nov;34(6):1037-62. doi: 10.1111/j.1574-6976.2010.00221.x.
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Identification of endophytic bacterial strain MGP1 selected from papaya and its biocontrol effects on pathogens infecting harvested papaya fruit.从木瓜中筛选出的内生细菌菌株 MGP1 的鉴定及其对采后木瓜果实病原菌的生物防治效果。
J Sci Food Agric. 2010 Jan 30;90(2):227-32. doi: 10.1002/jsfa.3798.
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Bioresour Technol. 2010 Jun;101(11):4089-95. doi: 10.1016/j.biortech.2009.12.143. Epub 2010 Feb 8.
8
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新型抗植物病原化合物 2-庚基-5-己基呋喃-3-羧酸，由新分离的假单胞菌 SJT25 菌株产生。

Novel antiphytopathogenic compound 2-heptyl-5-hexylfuran-3-carboxylic acid, produced by newly isolated Pseudomonas sp. strain SJT25.

机构信息

State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

出版信息

Appl Environ Microbiol. 2011 Sep;77(17):6253-7. doi: 10.1128/AEM.00443-11. Epub 2011 Jul 8.

DOI:10.1128/AEM.00443-11
PMID:21742907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3165416/
Abstract

Pseudomonas sp. strain SJT25, which strongly antagonizes plant pathogens, was isolated from rice rhizosphere soil by a bioactivity-guided approach. A novel antiphytopathogenic compound was isolated from the fermentation broth of Pseudomonas sp. SJT25 and identified as 2-heptyl-5-hexylfuran-3-carboxylic acid. This compound showed antimicrobial activities both in vitro and in vivo.

摘要

由生物活性导向的方法从水稻根际土壤中分离出一株强烈拮抗植物病原菌的假单胞菌（Pseudomonas sp.）菌株 SJT25。从假单胞菌 SJT25 的发酵液中分离得到一种新型抗植物病原菌化合物，鉴定为 2-庚基-5-己基呋喃-3-羧酸。该化合物在体外和体内均表现出抗菌活性。