Malaki Majid, Sayedzadeh Sayed Abolhassan, Shoaran Maryam
Pediatric Nephrology Department, Tabriz Medical University, Tabriz Children Hospital, Tabriz, Iran.
Saudi J Kidney Dis Transpl. 2011 Jul;22(4):723-6.
To determine the growth quality in children, less than 5 years of age, affected with urinary tract infection (UTI) and to compare the indices between patients with and without vesico-ureteral reflux (VUR) based on their reflux severity and/or laterality, we studied 106 children less than 5 years of age with UTI at Imam Reza Hospital of Kermanshah, Iran, and divided the study group into four subgroups based on their cystouretrography results as follows: Group 0: without reflux (as control group); Group 1: mild VUR; Group 2: moderate VUR; and Group 3: severe VUR. In all the subgroups, weight height index (WHI) was lower than 100% and was 96%, 93%, 95%, and 98%, respectively. We found no correlation between reflux severity and WHI in all the subgroups. In addition, the difference in the mean height standard deviation score (HSDS) (0.10, -0.12, -0.19, and -0.22, respectively) in the different subgroups was statistically insignificant. The mean WHI in the group with unilateral and bilateral reflux was 94.5% ± 8.9% and 95.0% ± 8.16%, respectively, while the mean HSDS was -0.16 ± 0.35 and -0.18 ± 0.38, respectively, and the difference was statistically insignificant in both the cases. We conclude that in children with UTI and normal glomerular filtration rate, the existence of reflux with all grades of severity and laterality exerts no impact on the growth index.
为了确定5岁以下患有尿路感染（UTI）儿童的生长质量，并根据膀胱输尿管反流（VUR）的严重程度和/或单侧性，比较有反流和无反流患者之间的指标，我们研究了伊朗克尔曼沙赫伊玛目礼萨医院106名5岁以下患有UTI的儿童，并根据膀胱尿道造影结果将研究组分为四个亚组，具体如下：0组：无反流（作为对照组）；1组：轻度VUR；2组：中度VUR；3组：重度VUR。在所有亚组中，体重身高指数（WHI）均低于100%，分别为96%、93%、95%和98%。我们发现所有亚组中反流严重程度与WHI之间均无相关性。此外，不同亚组的平均身高标准差评分（HSDS）（分别为0.10、-0.12、-0.19和-0.22）差异无统计学意义。单侧和双侧反流组的平均WHI分别为94.5%±8.9%和95.0%±8.16%，而平均HSDS分别为-0.16±0.35和-0.18±0.38，两种情况的差异均无统计学意义。我们得出结论，在UTI且肾小球滤过率正常的儿童中，不同严重程度和单侧性的反流对生长指标均无影响。
