Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Curr Opin Gastroenterol. 2011 Sep;27(5):407-11. doi: 10.1097/MOG.0b013e328349e240.
Gastroenterologists will likely play a critical role in the treatment of obesity and its comorbidities, as novel endoluminal approaches demonstrate their safety and efficacy over the coming years. Understanding the relative advantages and shortcomings of the endoscopic tools and procedures currently under investigation will provide the gastroenterologist with valuable insight into the future of endoscopic procedures for weight loss.
Endoscopic restrictive procedures, intestinal sleeves, and intragastric balloons have demonstrated short-term efficacy in inducing weight reduction and in reversing the comorbidities of obesity with an acceptable risk profile. Several endoscopic tools have also demonstrated effectiveness as revisional tools for reversing weight gain after bariatric surgery.
A plethora of endoscopic tools and procedures are under investigation for primary and revisional obesity management, and these may offer new weight loss options to a variety of different patient populations.
随着新型内镜治疗方法在未来几年内证明其安全性和有效性,胃肠病学家可能在肥胖及其合并症的治疗中发挥关键作用。了解当前正在研究的内镜工具和程序的相对优势和缺点,将为胃肠病学家提供有价值的见解,了解内镜减肥手术的未来。
内镜限制术、肠套叠和胃内球囊已证明在短期诱导体重减轻和逆转肥胖合并症方面具有疗效,同时风险状况可接受。一些内镜工具也已被证明可作为减重手术后体重反弹的修正工具。
大量的内镜工具和程序正在被研究用于原发性和修正性肥胖管理,这些可能为各种不同的患者群体提供新的减肥选择。