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小唾液腺腺样囊性癌的流行病学和治疗:荟萃分析研究。

Epidemiology and treatment of adenoid cystic carcinoma of the minor salivary glands: a meta-analytic study.

机构信息

Department of Surgery and Orofacial Implantology at the University Hospital of Madrid, Madrid 28015, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2011 Nov 1;16(7):e884-9. doi: 10.4317/medoral.17200.

DOI:10.4317/medoral.17200
PMID:21743416
Abstract

OBJECTIVES

To evaluate the epidemiological aspects of adenoid cystic carcinoma (ACC) and to evaluate the different therapeutic possibilities as well as the percentage of survival.

STUDY DESIGN

A retrospective, meta-analytic, observational study was carried out by selecting a total of 13 articles, which provided a sample size of 263 cases of patients who had been diagnosed with ACC in the minor salivary glands.

RESULTS

ACC was found to be more common among women (56.5%) and the average age at diagnosis was 55.26 years old. The primary location of the tumor was in the palate in 57% of the cases, the predominant pattern being cribiform. The treatment of choice was therapy combined with surgery and radiotherapy in 62.7% of the subjects. The overall survival rate was 70.76% and 56.76%, at 5 and 10 years respectively.

CONCLUSIONS

Early detection of adenoid cystic carcinoma is necessary in order to enable making an earlier prognosis and thus enable a better quality of life for the patient.

摘要

目的

评估腺样囊性癌(ACC)的流行病学特征,并评估不同的治疗可能性以及生存率。

研究设计

通过选择总共 13 篇文章进行回顾性、荟萃分析、观察性研究,这些文章提供了 263 例被诊断为小唾液腺 ACC 的患者样本量。

结果

ACC 更常见于女性(56.5%),诊断时的平均年龄为 55.26 岁。肿瘤的主要部位为 57%的病例中的 palate,主要模式为 cribiform。治疗选择是手术联合放疗的综合治疗,占 62.7%的患者。总体生存率分别为 70.76%和 56.76%,在 5 年和 10 年时。

结论

早期发现腺样囊性癌是必要的,以便能够进行更早的预后,从而为患者提供更好的生活质量。

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